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Elevating the discourse on drug delivery: A fresh perspective on the utilization of coordination chemistry-driven metal-drug conjugates
The drug development paradigm needed a significant shift towards utilizing bio-compatible
metal ions to stabilize potent drugs and enable their stimuli-responsive release. Highly …
metal ions to stabilize potent drugs and enable their stimuli-responsive release. Highly …
Multi-faceted antimicrobial efficacy of a quinoline-derived bidentate copper (II) ligand complex and its hydrogel encapsulated formulation in methicillin-resistant …
The emergence of antimicrobial resistance, exemplified by methicillin-resistant
Staphylococcus aureus (MRSA), poses a grave threat to public health globally. Over time …
Staphylococcus aureus (MRSA), poses a grave threat to public health globally. Over time …
Cytotoxic Cu (II) complexes with a novel quinoline derivative ligand: synthesis, molecular docking, and biological activity analysis
The utilization of metallodrugs as a viable alternative to organic molecules has gained
significant attention in modern medicine. We hereby report synthesis of new imine quinoline …
significant attention in modern medicine. We hereby report synthesis of new imine quinoline …
Chromophore appended DPA-based copper (ii) complexes with a diimine motif towards DNA binding and fragmentation studies
Mixed ligand copper (II) complexes [Cu (L1)(bpy)](ClO4) 21 and [Cu (L2)(bpy)](ClO4) 22
(where L1= 1-(anthracen-9-yl)-N, N-bis (pyridin-2-ylmethyl) methanamine, L2= 1-(pyren-1 …
(where L1= 1-(anthracen-9-yl)-N, N-bis (pyridin-2-ylmethyl) methanamine, L2= 1-(pyren-1 …
Unusual Ni⋯ Ni interaction in Ni (II) complexes as potential inhibitors for the development of new anti-SARS-CoV-2 Omicron drugs
Two nickel (II) coordination complexes [Ni (L)] 2 (1) and [Ni (L)] n (2) of a tetradentate Schiff
base ligand (H2L) derived from 2-hydroxy-1-naphthaldehyde with ethylenediamine were …
base ligand (H2L) derived from 2-hydroxy-1-naphthaldehyde with ethylenediamine were …
Crystal structure, ferromagnetic coupling and antibacterial activity of a new family of dicopper (II) complexes supported by auxiliary para-substituted benzoate linkers
In work to investigate the biologically active transition metal complexes, a new family of
ferromagnetically coupled dicopper (II) complexes (1–3) were synthesized and structurally …
ferromagnetically coupled dicopper (II) complexes (1–3) were synthesized and structurally …
SC-XRD investigation of Oh dicationic [CuII (Py2C (OH) 2) 2] 2+: A significant Jahn Teller distortion, 2D-S12/S9/S7 synthons, XRD/HSA-interactions, thermal …
A AlAli, K Shalalin, A Abu-Rayyan, H Khamees… - Journal of Molecular …, 2025 - Elsevier
Abstract Treating of Cu (NO 3) 2· 3H 2 O with di (pyridin-2-yl) methanone (Py 2 Cdouble
bondO) ligand resulted the [Cu II (Py 2 CO) 2](NO 3) 2 intermediate complex was first …
bondO) ligand resulted the [Cu II (Py 2 CO) 2](NO 3) 2 intermediate complex was first …
Emergence of an unconventional Enterobacter cloacae-derived Iturin A C-15 as a potential therapeutic agent against methicillin-resistant Staphylococcus aureus
Antimicrobial resistance poses a significant global health threat by reducing the
effectiveness of conventional antibiotics, particularly against pathogens like Methicillin …
effectiveness of conventional antibiotics, particularly against pathogens like Methicillin …
[HTML][HTML] Synthesis, Jahn-Teller labeled via crystal structure in trans-(ClO4) 2CuII (Me2N-Py) 4 complex: S9/S6/CH… O synthons, thermal, physicochemical and 1BNA …
A AlAli, A AlObaid, BS Chethan, K Shalalin… - Journal of King Saud …, 2024 - Elsevier
The synthesis of the trans-(ClO 4) 2 Cu II (Me 2 N-Py) 4 complex (where Me 2 N-Py= N, N-
dimethylpyridin-4-amine ligand) in significant yield involved the reaction of excess Me 2 N …
dimethylpyridin-4-amine ligand) in significant yield involved the reaction of excess Me 2 N …
Anti‐Malarial and Multi‐Bioactive Co (II), Cu (II) and Ni (II) Salen Complexes: Synthesis, Characterization and Computational Studies
MA Todarwal, RS Sancheti, SR Nikume… - Chemistry & …, 2024 - Wiley Online Library
Herein, we report the anti‐malarial, anti‐bacterial and anti‐inflammatory activities of the
N2O2 donor tetradentate salen type ligand and its CoL, NiL, and CuL metal complexes. The …
N2O2 donor tetradentate salen type ligand and its CoL, NiL, and CuL metal complexes. The …