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Dynamics of proteins in solution
The dynamics of proteins in solution includes a variety of processes, such as backbone and
side-chain fluctuations, interdomain motions, as well as global rotational and translational …
side-chain fluctuations, interdomain motions, as well as global rotational and translational …
[HTML][HTML] Modeling the Dynamics of Protein–Protein Interfaces, How and Why?
Protein–protein assemblies act as a key component in numerous cellular processes. Their
accurate modeling at the atomic level remains a challenge for structural biology. To address …
accurate modeling at the atomic level remains a challenge for structural biology. To address …
Structure and dynamics of G-protein coupled receptors
G-protein coupled receptors (GPCRs) are seven helical transmembrane proteins that
mediate cell-to-cell communication. They also form the largest superfamily of drug targets …
mediate cell-to-cell communication. They also form the largest superfamily of drug targets …
Mechanisms for the control of local tissue blood flow during thermal interventions: influence of temperature‐dependent ATP release from human blood and endothelial …
New Findings What is the central question of this study? Skin and muscle blood flow
increases with heating and decreases with cooling, but the temperature‐sensitive …
increases with heating and decreases with cooling, but the temperature‐sensitive …
Analysis of biosurfaces by neutron reflectometry: From simple to complex interfaces
Because of its high sensitivity for light elements and the scattering contrast manipulation via
isotopic substitutions, neutron reflectometry (NR) is an excellent tool for studying the …
isotopic substitutions, neutron reflectometry (NR) is an excellent tool for studying the …
Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?
Packed with hemoglobin, an essential protein for oxygen transport, human erythrocytes are
a suitable model system for testing the pleiotropic effects of lipophilic drugs. Our study …
a suitable model system for testing the pleiotropic effects of lipophilic drugs. Our study …
Regional thermal hyperemia in the human leg: Evidence of the importance of thermosensitive mechanisms in the control of the peripheral circulation
Hyperthermia is thought to increase limb blood flow through the activation of thermosensitive
mechanisms within the limb vasculature, but the precise vascular locus in which …
mechanisms within the limb vasculature, but the precise vascular locus in which …
Hemoglobin–PEG Interactions Probed by Small-Angle X-ray Scattering: Insights for Crystallization and Diagnostics Applications
I Baranova, A Angelova, J Stransky… - The Journal of …, 2024 - ACS Publications
Protein–protein interactions, controlling protein aggregation in the solution phase, are
crucial for the formulation of protein therapeutics and the use of proteins in diagnostic …
crucial for the formulation of protein therapeutics and the use of proteins in diagnostic …
Effect of red blood cell shape changes on haemoglobin interactions and dynamics: a neutron scattering study
By using a combination of experimental neutron scattering techniques, it is possible to
obtain a statistical perspective on red blood cell (RBC) shape in suspensions, and the inter …
obtain a statistical perspective on red blood cell (RBC) shape in suspensions, and the inter …
Molecular adaptation and salt stress response of Halobacterium salinarum cells revealed by neutron spectroscopy
Halobacterium salinarum is an extreme halophile archaeon with an absolute requirement for
a multimolar salt environment. It accumulates molar concentrations of KCl in the cytosol to …
a multimolar salt environment. It accumulates molar concentrations of KCl in the cytosol to …