Dynamics of proteins in solution

M Grimaldo, F Roosen-Runge, F Zhang… - Quarterly Reviews of …, 2019 - cambridge.org
The dynamics of proteins in solution includes a variety of processes, such as backbone and
side-chain fluctuations, interdomain motions, as well as global rotational and translational …

[HTML][HTML] Modeling the Dynamics of Protein–Protein Interfaces, How and Why?

E Karaca, C Prévost, S Sacquin-Mora - Molecules, 2022 - mdpi.com
Protein–protein assemblies act as a key component in numerous cellular processes. Their
accurate modeling at the atomic level remains a challenge for structural biology. To address …

Structure and dynamics of G-protein coupled receptors

N Vaidehi, S Bhattacharya, AB Larsen - G Protein-Coupled Receptors …, 2014 - Springer
G-protein coupled receptors (GPCRs) are seven helical transmembrane proteins that
mediate cell-to-cell communication. They also form the largest superfamily of drug targets …

Mechanisms for the control of local tissue blood flow during thermal interventions: influence of temperature‐dependent ATP release from human blood and endothelial …

KK Kalsi, ST Chiesa, SJ Trangmar, L Ali… - Experimental …, 2017 - Wiley Online Library
New Findings What is the central question of this study? Skin and muscle blood flow
increases with heating and decreases with cooling, but the temperature‐sensitive …

Analysis of biosurfaces by neutron reflectometry: From simple to complex interfaces

A Junghans, EB Watkins, RD Barker, S Singh… - …, 2015 - pubs.aip.org
Because of its high sensitivity for light elements and the scattering contrast manipulation via
isotopic substitutions, neutron reflectometry (NR) is an excellent tool for studying the …

Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?

L Platanić Arizanović, N Gligorijević, I Cvijetić… - International Journal of …, 2023 - mdpi.com
Packed with hemoglobin, an essential protein for oxygen transport, human erythrocytes are
a suitable model system for testing the pleiotropic effects of lipophilic drugs. Our study …

Regional thermal hyperemia in the human leg: Evidence of the importance of thermosensitive mechanisms in the control of the peripheral circulation

N Koch Esteves, OR Gibson, AW Khir… - Physiological …, 2021 - Wiley Online Library
Hyperthermia is thought to increase limb blood flow through the activation of thermosensitive
mechanisms within the limb vasculature, but the precise vascular locus in which …

Hemoglobin–PEG Interactions Probed by Small-Angle X-ray Scattering: Insights for Crystallization and Diagnostics Applications

I Baranova, A Angelova, J Stransky… - The Journal of …, 2024 - ACS Publications
Protein–protein interactions, controlling protein aggregation in the solution phase, are
crucial for the formulation of protein therapeutics and the use of proteins in diagnostic …

Effect of red blood cell shape changes on haemoglobin interactions and dynamics: a neutron scattering study

K Shou, M Sarter, NR De Souza… - Royal Society …, 2020 - royalsocietypublishing.org
By using a combination of experimental neutron scattering techniques, it is possible to
obtain a statistical perspective on red blood cell (RBC) shape in suspensions, and the inter …

Molecular adaptation and salt stress response of Halobacterium salinarum cells revealed by neutron spectroscopy

P Vauclare, V Marty, E Fabiani, N Martinez, M Jasnin… - Extremophiles, 2015 - Springer
Halobacterium salinarum is an extreme halophile archaeon with an absolute requirement for
a multimolar salt environment. It accumulates molar concentrations of KCl in the cytosol to …