Water dynamics in the hydration shells of biomolecules

D Laage, T Elsaesser, JT Hynes - Chemical Reviews, 2017 - ACS Publications
The structure and function of biomolecules are strongly influenced by their hydration shells.
Structural fluctuations and molecular excitations of hydrating water molecules cover a broad …

Molecular crowding effects on structure and stability of DNA

D Miyoshi, N Sugimoto - Biochimie, 2008 - Elsevier
Living cells contain a variety of biomolecules including nucleic acids, proteins,
polysaccharides, and metabolites as well as other soluble and insoluble components. These …

Biomolecular electrostatics and solvation: a computational perspective

P Ren, J Chun, DG Thomas, MJ Schnieders… - Quarterly reviews of …, 2012 - cambridge.org
An understanding of molecular interactions is essential for insight into biological systems at
the molecular scale. Among the various components of molecular interactions, electrostatics …

Dynamical disorder in the DNA hydration shell

E Duboué-Dijon, AC Fogarty, JT Hynes… - Journal of the American …, 2016 - ACS Publications
The reorientation and hydrogen-bond dynamics of water molecules within the hydration
shell of a B-DNA dodecamer, which are of interest for many of its biochemical functions, are …

Revisiting macromolecular hydration with HullRadSAS

PJ Fleming, JJ Correia, KG Fleming - European Biophysics Journal, 2023 - Springer
Hydration of biological macromolecules is important for their stability and function.
Historically, attempts have been made to describe the degree of macromolecular hydration …

[HTML][HTML] AFM volumetric methods for the characterization of proteins and nucleic acids

ME Fuentes-Perez, MS Dillingham, F Moreno-Herrero - Methods, 2013 - Elsevier
The atomic force microscope overestimates lateral dimensions and underestimates heights
of nanometer size objects such as proteins and nucleic acids. This has made researchers …

Detection of nucleotides in hydrated ssDNA via 2D h‐BN nanopore with ionic‐liquid/salt–water interface

JS Lee, JP Oviedo, YMNDY Bandara, X Peng… - …, 2021 - Wiley Online Library
Accomplishing slow translocation speed with high sensitivity has been the most critical
mission for solid‐state nanopore (SSN) device to electrically detect nucleobases in ssDNA …

Unravelling a mechanism of action for a cecropin A-melittin hybrid antimicrobial peptide: the induced formation of multilamellar lipid stacks

T Silva, B Claro, BFB Silva, N Vale, P Gomes… - Langmuir, 2018 - ACS Publications
An understanding of the mechanism of action of antimicrobial peptides is fundamental to the
development of new and more active antibiotics. In the present work, we use a wide range of …

Hydration changes accompanying helix-to-coil DNA transitions

I Son, YL Shek, DN Dubins… - Journal of the American …, 2014 - ACS Publications
We applied ultrasonic velocimetric and high-precision densimetric measurements to
characterizing the helix-to-coil transition of the GGCATTACGG/CCGTAATGCC decameric …

Effect of ethylene glycol, urea, and N-methylated glycines on DNA thermal stability: the role of DNA base pair composition and hydration

LJ Nordstrom, CA Clark, B Andersen, SM Champlin… - Biochemistry, 2006 - ACS Publications
The accumulation of the cosolutes ethylene glycol, urea, glycine, sarcosine, and glycine
betaine at the single-stranded DNA surface exposed upon melting the double helix has …