Tissue‐scale biomechanical testing of brain tissue for the calibration of nonlinear material models

J Faber, J Hinrichsen, A Greiner, N Reiter… - Current …, 2022 - Wiley Online Library
Brain tissue is one of the most complex and softest tissues in the human body. Due to its
ultrasoft and biphasic nature, it is difficult to control the deformation state during …

Distinguishing poroelasticity and viscoelasticity of brain tissue with time scale

L Su, M Wang, J Yin, F Ti, J Yang, C Ma, S Liu, TJ Lu - Acta biomaterialia, 2023 - Elsevier
Brain tissue is considered to be biphasic, with approximately 80% liquid and 20% solid
matrix, thus exhibiting viscoelasticity due to rearrangement of the solid matrix and …

Inverse identification of region-specific hyperelastic material parameters for human brain tissue

J Hinrichsen, N Reiter, L Bräuer, F Paulsen… - … and Modeling in …, 2023 - Springer
The identification of material parameters accurately describing the region-dependent
mechanical behavior of human brain tissue is crucial for computational models used to …

Compressive response of white matter in the brain at low strain rates

L Su, B Qi, J Yin, X Qin, GM Genin, S Liu… - International Journal of …, 2024 - Elsevier
The low strain-rate response of brain parenchyma is critical to predicting prognosis in cases
of hydrocephalus or cerebral edema, including in the prediction of brain stem herniation …

[HTML][HTML] On the importance of using region-dependent material parameters for full-scale human brain simulations

E Griffiths, J Hinrichsen, N Reiter, S Budday - European Journal of …, 2023 - Elsevier
An accurate finite element (FE) model of the human brain reliably predicting its response to
loading offers great possibilities for brain injury prevention, disease prediction, and surgical …

Mechanical behavior and constitutive equations of porcine brain tissue considering both solution environment effect and strain rate effect

J Wang, Y Zhang, Z Jiang, L Zhou, Z Liu… - Mechanics of …, 2024 - Taylor & Francis
Because brain tissue is immersed in cerebrospinal fluid, and studies such as TBI (traumatic
brain injury) include impact mechanical properties of brain tissue, the constitutive relation of …

Mechanical characteristics of glioblastoma and peritumoral tumor-free human brain tissue

J Kren, I Skambath, P Kuppler, S Buschschlüter… - Acta …, 2024 - Springer
Background The diagnosis of brain tumor is a serious event for the affected patient. Surgical
resection is a crucial part in the treatment of brain tumors. However, the distinction between …

Assessment of the Behaviors of an In Vitro Brain Model On-Chip under Shockwave Impacts

MF Rubby, C Fonder, S Uchayash… - … Applied Materials & …, 2024 - ACS Publications
Herein we report the assessment of the effects of shockwave (SW) impacts on adult rat
hippocampal progenitor cell (AHPC) neurospheres (NSs), which are used as in vitro brain …

Acute brain slice elastic modulus decreases over time

J Exton, JMG Higgins, J Chen - Scientific Reports, 2023 - nature.com
A common benchmark in the brain tissue mechanics literature is that the properties of acute
brain slices should be measured within 8 h of the experimental animal being sacrificed. The …

Mechanical behavior and microstructure of porcine brain tissues under pulsed electric fields

Y Li, Q Zhang, J Zhao, Z Wang, X Zong, L Yang… - … and Modeling in …, 2024 - Springer
Pulsed electric fields are extensively utilized in clinical treatments, such as subthalamic
deep brain stimulation, where electric field loading is in direct contact with brain tissue …