Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants

M Tiwari, E Gas-Pascual, M Goyal, M Popov… - mSphere, 2025 - journals.asm.org
Cellular adaptations to change often involve post-translational modifications of nuclear and
cytoplasmic proteins. An example found in protists and plants is the modification of serine …

Glycosylation of Skp1 promotes formation of Skp1–cullin-1–F-box protein complexes in Dictyostelium

MO Sheikh, Y Xu, H van der Wel, P Walden… - Molecular & Cellular …, 2015 - ASBMB
O 2 sensing in diverse protozoa depends on the prolyl 4 hydroxylation of Skp1 and
modification of the resulting hydroxyproline with a series of five sugars. In yeast, plants, and …

Skp1 isoforms are differentially modified by a dual function prolyl 4-hydroxylase/N-acety lglucosaminyltransferase in a plant pathogen

H van der Wel, E Gas-Pascual, CM West - Glycobiology, 2019 - academic.oup.com
Skp1 is hydroxylated by an O2-dependent prolyl hydroxylase (PhyA) that contributes to O2-
sensing in the social amoeba Dictyostelium and the mammalian pathogen Toxoplasma …