Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)

JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

[BOOK][B] Microcomputed tomography: methodology and applications

SR Stock - 2019 - taylorfrancis.com
MicroComputed Tomography has become the gold standard for studying 3D microscopic
structures nondestructively, and this book provides up-to-date coverage of the modality. The …

Early imaging signs of the use of antiresorptive medication and MRONJ: a systematic review

C Moreno-Rabié, H Gaêta-Araujo… - Clinical oral …, 2020 - Springer
Objective The main aim is to identify, by means of different imaging modalities, the early
bone changes in patients “at risk” and in stage 0 MRONJ. Materials and methods A search of …

Pathogenesis of medication-related osteonecrosis of the jaw: a comparative study of in vivo and in vitro trials

H Holtmann, J Lommen, NR Kübler… - Journal of …, 2018 - journals.sagepub.com
Objective This study was performed to determine whether the results of prevailing in vivo
and in vitro studies offer a reliable model for investigation of medication-related …

Obesity influences the development of bisphosphonate-induced osteonecrosis in Wistar rats

WJM Lima, JCX PONTES, LS FIGUEIREDO… - Journal of Applied Oral …, 2023 - SciELO Brasil
Medication-related osteonecrosis of the jaw (MRONJ) is characterized by bone exposure for
more than eight weeks in patients who have used or been treated with antiresorptive or …

Influence of antiresorptive/antiangiogenic therapy on the extension of experimentally induced peri-implantitis lesions

F Schwarz, K Becker, F Lukman, KM Müller… - Clinical oral …, 2023 - Springer
Objectives To investigate the extension of experimentally induced peri-implantitis lesions
under various antiresorptive and antiangiogenic medications. Material and methods Fourty …

Microarchitecture of medication-related osteonecrosis of the jaw (MRONJ); a retrospective micro-CT and morphometric analysis

R Schoenhof, A Munz, A Yuan, A ElAyouti… - Journal of Cranio …, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a severe side effect of antiresorptive
(AR) drugs such as bisphosphonates (BP) and denosumab (Dmab). Although several risk …

The effect of risedronate on orthodontic tooth movement in ovariectomized rats

D Wu, B Meng, Y Cheng, L Gan, P Huang, Y Cao - Archives of Oral Biology, 2019 - Elsevier
Objective This study aimed to investigate the effect of risedronate on orthodontic tooth
movement in ovariectomized rats. Methods Forty-five female Sprague-Dawley rats were …

Why do some extraction sites develop medication-related osteonecrosis of the jaw and others do not? A within-patient study assessing radiographic predictors.

H Gaêta-Araujo, A Ferreira Leite… - … Journal of Oral …, 2021 - search.ebscohost.com
Purpose: To compare radiographic predictors of medication-related osteonecrosis of the jaw
in dental extraction sites. Materials and methods: Forty-one oncological patients undergoing …

Significance of medication discontinuation on bisphosphonate-related jaw osteonecrosis in a rat model

KR Mustakim, MY Eo, JH Oh, JY Lee, H Myoung… - Scientific reports, 2022 - nature.com
Bisphosphonate (BP) discontinuation has been advised as a measure to prevent the
incidence of bisphosphonate-related osteonecrosis of the jaw (BRONJ), however, its efficacy …