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[HTML][HTML] Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies
Objective Fracture-related infection (FRI) remains a major concern in orthopaedic trauma.
Functionalizing implants with antibacterial coatings are a promising strategy in mitigating …
Functionalizing implants with antibacterial coatings are a promising strategy in mitigating …
Exploring the application of Graphene Oxide-based nanomaterials in the repair of osteoporotic fractures
H Zhou, J Chen, X Zhang, JJ Chen, J Chen, S Jia… - Nanomaterials, 2024 - mdpi.com
Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of
bone tissues and microstructures and impair their healing ability. Conventional internal …
bone tissues and microstructures and impair their healing ability. Conventional internal …
[HTML][HTML] Biodegradable Zn-2Cu-0.5 Zr alloy promotes the bone repair of senile osteoporotic fractures via the immune-modulation of macrophages
H Ji, G Shen, H Liu, Y Liu, J Qian, GJ Wan, E Luo - Bioactive Materials, 2024 - Elsevier
Delayed bone-healing of senile osteoporotic fractures remains a clinical challenge due to
the alterations caused by aging in bone and immune systems. The novel biomaterials that …
the alterations caused by aging in bone and immune systems. The novel biomaterials that …
A multifunctional scaffold for bone infection treatment by delivery of microRNA therapeutics combined with antimicrobial nanoparticles
Treating bone infections and ensuring bone repair is one of the greatest global challenges
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …
Synergistic combination of baicalein and rifampicin against Staphylococcus aureus biofilms
R Muniyasamy, I Manjubala - Frontiers in Microbiology, 2024 - frontiersin.org
Staphylococcus aureus, a Gram-positive bacterium, is a predominant pathogen associated
with various infections. The rapid emergence of antibiotic resistance has intensified the …
with various infections. The rapid emergence of antibiotic resistance has intensified the …
[HTML][HTML] Hydrogel delivery of DNase I and liposomal vancomycin to eradicate fracture-related methicillin-resistant staphylococcus aureus infection and support …
Fracture-related infection (FRI) is a devastating complication in orthopedic surgery. A recent
study showed that FRI causes more severe infection and further delays healing in …
study showed that FRI causes more severe infection and further delays healing in …
Bioactive composite hydrogel with effects of robust promoting osteogenesis and immunomodulation for osteoporotic bone regeneration
B Sun, H Wang, B **ao, H Yan, H Wu, R Zhang… - Chemical Engineering …, 2023 - Elsevier
Osteoporotic bone defect is an intractable challenge in clinical practice, involving impaired
bone repair ability and abnormal immune response. Despite the development of various …
bone repair ability and abnormal immune response. Despite the development of various …
Preventing septic implant failures in osteoporotic hip fractures using antibiotic-loaded functionalized nanocement
Osteoporosis is a prevalent skeletal disorder and the most common cause of debilitating hip
fractures, primarily affecting post-menopausal women and elderly people. Implants used to …
fractures, primarily affecting post-menopausal women and elderly people. Implants used to …
[HTML][HTML] Effects of aging on osteosynthesis at bone–implant interfaces
Joint replacement is a common surgery and is predominantly utilized for treatment of
osteoarthritis in the aging population. The longevity of many of these implants depends on …
osteoarthritis in the aging population. The longevity of many of these implants depends on …
A population-based epidemiological and health economic analysis of fracture-related infection
Aims The aim of this study was to perform the first population-based description of the
epidemiological and health economic burden of fracture-related infection (FRI). Methods …
epidemiological and health economic burden of fracture-related infection (FRI). Methods …