Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

The role of curcumin in cancer: a focus on the PI3K/Akt pathway

V Zoi, AP Kyritsis, V Galani, D Lazari, C Sioka… - Cancers, 2024 - mdpi.com
Simple Summary Cancer has a major impact on societies across the world. In an attempt to
find new treatment options for cancer, attention has shifted to natural compounds. Curcumin …

Curcumin can improve Parkinson's disease via activating BDNF/PI3k/Akt signaling pathways

T **, Y Zhang, BOA Botchway, J Zhang, R Fan… - Food and Chemical …, 2022 - Elsevier
Parkinson's disease is a common progressive neurodegenerative disease, and presently
has no curative agent. Curcumin, as one of the natural polyphenols, has great potential in …

Turmeric and its bioactive constituents trigger cell signaling mechanisms that protect against diabetes and cardiovascular diseases

HA Zhang, DD Kitts - Molecular and cellular biochemistry, 2021 - Springer
Turmeric, the rhizome of Curcuma longa plant belonging to the ginger family Zingiberaceae,
has a history in Ayurvedic and traditional Chinese medicine for treatment of chronic …

Curcumin in cancer therapy: A novel adjunct for combination chemotherapy with paclitaxel and alleviation of its adverse effects

M Ashrafizadeh, A Zarrabi, F Hashemi, ER Moghadam… - Life sciences, 2020 - Elsevier
Dealing with cancer is of importance due to enhanced incidence rate of this life-threatening
disorder. Chemotherapy is an ideal candidate in overcoming and eradication of cancer. To …

Molecular mechanism of curcumin action in signaling pathways: Review of the latest research

P Liczbiński, J Michałowicz… - Phytotherapy …, 2020 - Wiley Online Library
Recently, many studies have been conducted trying to explain the molecular mechanism of
curcumin action in various pathological states of the cell and the organism. Curcumin is …

[HTML][HTML] Combination anticancer therapies using selected phytochemicals

WH Talib, D Awajan, RA Hamed, AO Azzam… - Molecules, 2022 - mdpi.com
Cancer is still one of the most widespread diseases globally, it is considered a vital health
challenge worldwide and one of the main barriers to long life expectancy. Due to the …

The power of phytochemicals combination in cancer chemoprevention

B Rizeq, I Gupta, J Ilesanmi, M AlSafran… - Journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Conventional therapies for cancer treatment have posed many challenges, including toxicity,
multidrug resistance and economic expenses. In contrast, complementary alternative …

Folate-modified carboxymethyl chitosan-based drug delivery system for breast cancer specific combination therapy via regulating mitochondrial calcium concentration

Y Lv, X Chen, Y Shen - Carbohydrate polymers, 2024 - Elsevier
Although various drug delivery systems that regulated Ca 2+ concentration has been
developed for tumor therapy, their application still presented significant challenges due to …

The involvement of natural polyphenols in molecular mechanisms inducing apoptosis in tumor cells: A promising adjuvant in cancer therapy

A Chimento, A De Luca, M D'Amico… - International Journal of …, 2023 - mdpi.com
Various literature data show how a diet rich in vegetables could reduce the incidence of
several cancers due to the contribution of the natural polyphenols contained in them …