Traumatic brain injury (TBI) is a leading cause of death and disability, and there are currently
no pharmacological treatments known to improve patient outcomes. Unquestionably …

Neurological heterotopic ossification (NHO) is a debilitating condition where bone forms in
soft tissue, such as muscle surrounding the hip and knee, following an injury to the brain or …

As brain and bone disorders represent major health issues worldwide, substantial clinical
investigations demonstrated a bidirectional crosstalk on several levels, mechanistically …

The orthopaedic community frequently encounters polytrauma individuals with concomitant
traumatic brain injury (TBI) and their fractures demonstrate accelerated fracture union, but …

Heterotopic ossification is defined as an aberrant formation of bone in extraskeletal soft
tissue, for which both genetic and acquired conditions are known. This pathologic process …

Abstract Purpose of Review Neurogenic heterotopic ossification (NHO) is the abnormal
formation of extra-skeletal bones in periarticular muscles after damage to the central …

Studies have indicated that concussive and sub-concussive brain injuries that are frequent
during collision sports may lead to long-term neurological abnormalities, however there is a …

A growing body of evidence suggests that patients who experience traumatic brain injuries
(TBIs) exhibit significantly shorter healing periods compared to those with isolated fractures …

Introduction: Serum neurofilament light (NfL) is an emerging biomarker of traumatic brain
injury (TBI). However, the effect of peripheral injuries such as long bone fracture and skeletal …

Neurogenic heterotopic ossification (NHO) is the formation of mature lamellar bone in peri-
articular tissues following a neurological insult, most commonly traumatic brain injury (TBI) …