[HTML][HTML] Epigenetics in susceptibility, progression, and diagnosis of periodontitis

S Suzuki, S Yamada - Japanese Dental Science Review, 2022 - Elsevier
Periodontitis is characterized by irreversible destruction of periodontal tissue. At present, the
accepted etiology of periodontitis is based on a three-factor theory including pathogenic …

Epigenetic regulation of osteogenic differentiation of periodontal ligament stem cells in periodontitis

J Cao, Q Zhang, Q Yang, Y Yu, M Meng, J Zou - Oral Diseases, 2023 - Wiley Online Library
Periodontitis is an inflammatory disease characterized by alveolar bone loss. Periodontal
ligament stem cells (PDLSCs) have osteogenic differentiation potential, which can be …

Automated large vessel occlusion detection software and thrombectomy treatment times: a cluster randomized clinical trial

JC Martinez-Gutierrez, Y Kim, S Salazar-Marioni… - JAMA …, 2023 - jamanetwork.com
Importance The benefit of endovascular stroke therapy (EVT) in large vessel occlusion
(LVO) ischemic stroke is highly time dependent. Process improvements to accelerate in …

Batch effect detection and correction in RNA-seq data using machine-learning-based automated assessment of quality

M Sprang, MA Andrade-Navarro, JF Fontaine - BMC bioinformatics, 2022 - Springer
Background The constant evolving and development of next-generation sequencing
techniques lead to high throughput data composed of datasets that include a large number …

[HTML][HTML] Next-generation examination, diagnosis, and personalized medicine in periodontal disease

T Kikuchi, J Hayashi, A Mitani - Journal of personalized medicine, 2022 - mdpi.com
Periodontal disease, a major cause of tooth loss, is an infectious disease caused by bacteria
with the additional aspect of being a noncommunicable disease closely related to lifestyle …

[HTML][HTML] The relevance of DNA methylation and histone modification in periodontitis: a sco** review

A Liaw, C Liu, S Ivanovski, P Han - Cells, 2022 - mdpi.com
Background: Periodontitis is a chronic inflammatory disease involving an interplay between
bacteria, inflammation, host response genes, and environmental factors. The manifestation …

Pyroptosis may play a crucial role in modifications of the immune microenvironment in periodontitis

H Chen, Z Wang, Y He, L Peng, J Zhu… - Journal of Periodontal …, 2022 - Wiley Online Library
Background and objective Published studies proved that both pyroptosis and periodontitis
owned a substantial relationship with immunity, and recent research revealed a solid …

Identification and validation of a classifier based on hub aging-related genes and aging subtypes correlation with immune microenvironment for periodontitis

L Peng, H Chen, Z Wang, Y He, X Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Background Periodontitis (PD), an age-related disease, is characterized by inflammatory
periodontal tissue loss, and with the general aging of the global population, the burden of …

Development of a classification model and an immune‐related network based on ferroptosis in periodontitis

Z Xu, R Tan, X Li, L Pan, P Ji… - Journal of periodontal …, 2023 - Wiley Online Library
Abstract Background and Objectives Periodontitis is an immunoinflammatory disease
characterized by irreversible periodontal attachment loss and bone destruction. Ferroptosis …

Methylome-wide analysis in systemic microbial-induced experimental periodontal disease in mice with different susceptibility

CJ Hernandez Martinez, J Glessner… - Frontiers in Cellular …, 2024 - frontiersin.org
Objective The study delved into the epigenetic factors associated with periodontal disease in
two lineages of mice, namely C57bl/6 and Balb/c. Its primary objective was to elucidate …