Role of vitamins and minerals as immunity boosters in COVID-19

P Kumar, M Kumar, O Bedi, M Gupta, S Kumar… - …, 2021 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) known as coronavirus
disease (COVID-19), emerged in Wuhan, China, in December 2019. On March 11, 2020, it …

Iodine: Its role in thyroid hormone biosynthesis and beyond

S Sorrenti, E Baldini, D Pironi, A Lauro, V D'Orazi… - Nutrients, 2021 - mdpi.com
The present review deals with the functional roles of iodine and its metabolism. The main
biological function of iodine concerns its role in the biosynthesis of thyroid hormones (THs) …

[HTML][HTML] Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense

MM Leiva-Juárez, JK Kolls, SE Evans - Mucosal immunology, 2018 - Elsevier
Lung epithelial cells are increasingly recognized to be active effectors of microbial defense,
contributing to both innate and adaptive immune function in the lower respiratory tract. As …

The Na+/I Symporter (NIS): Mechanism and Medical Impact

C Portulano, M Paroder-Belenitsky… - Endocrine …, 2014 - academic.oup.com
Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Potential roles of micronutrient deficiency and immune system dysfunction in the coronavirus disease 2019 (COVID-19) pandemic

A Gorji, MK Ghadiri - Nutrition, 2021 - Elsevier
Preliminary studies indicate that a robust immune response across different cell types is
crucial in recovery from coronavirus disease 2019 (COVID-19). An enormous number of …

Failure of respiratory defenses in the pathogenesis of bacterial pneumonia of cattle

JL Caswell - Veterinary pathology, 2014 - journals.sagepub.com
The respiratory system is well defended against inhaled bacteria by a dynamic system of
interacting layers, including mucociliary clearance, host defense factors including …

Role of iodide metabolism in physiology and cancer

A De la Vieja, P Santisteban - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Iodide (I−) metabolism is crucial for the synthesis of thyroid hormones (THs) in the thyroid
and the subsequent action of these hormones in the organism. I− is principally transported …

Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling

X De Deken, B Corvilain, JE Dumont… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Among the NADPH oxidases, the dual oxidases, DUOX1 and DUOX2,
constitute a distinct subfamily initially called thyroid oxidases, based on their high level of …

Antimicrobial actions of dual oxidases and lactoperoxidase

D Sarr, E Tóth, A Gingerich, B Rada - Journal of Microbiology, 2018 - Springer
The NOX/DUOX family of NADPH oxidases are transmembrane proteins generating reactive
oxygen species as their primary enzymatic products. NADPH oxidase (NOX) 1–5 and Dual …

Fluoride exposure induces inhibition of sodium/iodide symporter (NIS) contributing to impaired iodine absorption and iodine deficiency: molecular mechanisms of …

DT Waugh - International Journal of Environmental Research and …, 2019 - mdpi.com
The sodium iodide symporter (NIS) is the plasma membrane glycoprotein that mediates
active iodide transport in the thyroid and other tissues, such as the salivary, gastric mucosa …