Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

E Rossi, R La Rosa, JA Bartell, RL Marvig… - Nature Reviews …, 2021 - nature.com
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …

Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: roles and mechanisms

X Shi, Y **a, W Wei, BJ Ni - Water research, 2022 - Elsevier
The global spread of antibiotic resistance genes (ARGs) has wreaked havoc with the
treatment efficiency of antibiotics and, ultimately, anti-microbial chemotherapy, and has been …

Bacterial multidrug efflux pumps: much more than antibiotic resistance determinants

P Blanco, S Hernando-Amado, JA Reales-Calderon… - Microorganisms, 2016 - mdpi.com
Bacterial multidrug efflux pumps are antibiotic resistance determinants present in all
microorganisms. With few exceptions, they are chromosomally encoded and present a …

Antimicrobial silver: uses, toxicity and potential for resistance

K Mijnendonckx, N Leys, J Mahillon, S Silver… - Biometals, 2013 - Springer
This review gives a comprehensive overview of the widespread use and toxicity of silver
compounds in many biological applications. Moreover, the bacterial silver resistance …

Pseudomonas putida KT2440: the long journey of a soil-dweller to become a synthetic biology chassis

V de Lorenzo, D Pérez-Pantoja, PI Nikel - Journal of bacteriology, 2024 - journals.asm.org
Although members of the genus Pseudomonas share specific morphological, metabolic, and
genomic traits, the diversity of niches and lifestyles adopted by the family members is vast …

Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence

M Alcalde-Rico, S Hernando-Amado, P Blanco… - Frontiers in …, 2016 - frontiersin.org
Multidrug efflux pumps can be involved in bacterial resistance to antibiotics at different
levels. Some efflux pumps are constitutively expressed at low levels and contribute to …

Antibiotic resistance in urban runoff

A Almakki, E Jumas-Bilak, H Marchandin… - Science of the Total …, 2019 - Elsevier
Aquatic ecosystems subjected to anthropogenic pressures are places of rapid evolution of
microbial communities and likely hotspots for selection and emergence of antibiotic resistant …

The role of natural environments in the evolution of resistance traits in pathogenic bacteria

JL Martinez - Proceedings of the Royal Society B …, 2009 - royalsocietypublishing.org
Antibiotics are among the most valuable compounds used for fighting human diseases.
Unfortunately, pathogenic bacteria have evolved towards resistance. One important and …

The rhizosphere as a reservoir for opportunistic human pathogenic bacteria

G Berg, L Eberl, A Hartmann - Environmental microbiology, 2005 - Wiley Online Library
During the last years, the number of human infections caused by opportunistic pathogens
has increased dramatically. One natural reservoir of opportunistic pathogens is the …

Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa

M Valentini, D Gonzalez, DAI Mavridou… - Current opinion in …, 2018 - Elsevier
Highlights•Pseudomonas aeruginosa causes acute and chronic infections in
humans.•Virulence factors are co-regulated with lifestyles.•The Gac/Rsm cascade regulates …