Cell migration is a highly dynamic process driven by the cytoskeleton, which mainly
comprises the actin microfilaments, microtubules, and intermediate filaments. During …

Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

The ability of animal cells to sense, adhere to and remodel their local extracellular matrix
(ECM) is central to control of cell shape, mechanical responsiveness, motility and signalling …

Integrins are heterodimeric cell surface receptors composed of α and β subunits that control
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …

Simple Summary The microtubule (MT) cytoskeleton is a crucial factor for organized cell
motility and migration of cancer as well as benign cells. Mitotic centromere-associated …

Cadherins and integrins are intrinsically linked through the actin cytoskeleton and are
largely responsible for the mechanical integrity and organization of tissues. We show that …

MicroRNAs (miRNAs) are small, non-coding RNAs about 22 nucleotides in length that
regulate the expression of target genes post-transcriptionally, and are highly involved in …

Actin cytoskeleton dynamics are essential regulatory processes in muscle development,
growth, and regeneration due to their modulation of mechanotransduction, cell proliferation …

Nascent adhesions are submicron transient structures promoting the early adhesion of cells
to the extracellular matrix. Nascent adhesions typically consist of several tens of integrins …

Abstract Background The R-RAS2 is a small GTPase highly similar to classical RAS proteins
at the regulatory and signaling levels. The high evolutionary conservation of R-RAS2, its …