We have come a long way in the last years of develo** analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

The rapid emergence of metabolomics has enabled system-wide measurements of
metabolites in various organisms. However, advances in the mechanistic understanding of …

Background Untargeted metabolomics generates a huge amount of data. Software
packages for automated data processing are crucial to successfully process these data. A …

Liquid chromatography (LC) coupled with mass spectrometry (MS) is widely used for the
determination of mycotoxins in cereals and cereal-based products. In addition to the …

Studies of isotopically labeled compounds have been fundamental to understanding
metabolic pathways and fluxes. They have traditionally, however, been used in conjunction …

Untargeted metabolomics can detect more than 10 000 peaks in a single LC–MS run. The
correspondence between these peaks and metabolites, however, remains unclear. Here, we …

The identification of small molecules from mass spectrometry (MS) data remains a major
challenge in the interpretation of MS data. This review covers the computational aspects of …

Abstract System-wide metabolic homeostasis is crucial for maintaining physiological
functions of living organisms. Stable-isotope tracing metabolomics allows to unravel …

In natural-product drug discovery, finding new compounds is the main task, and thus fast
dereplication of known compounds is essential. This is usually performed by manual liquid …

A chemical isotope labeling or isotope coded derivatization (ICD) metabolomics platform
uses a chemical derivatization method to introduce a mass tag to all of the metabolites …