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[HTML][HTML] Proteogenomic characterization of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …
survival. Toward understanding the underlying molecular alterations that drive PDAC …
Screening for pancreatic cancer has the potential to save lives, but is it practical?
Introduction Most patients with pancreatic cancer present with advanced stage, incurable
disease. However, patients with high-grade precancerous lesions and many patients with …
disease. However, patients with high-grade precancerous lesions and many patients with …
A critical review of datasets and computational suites for improving cancer theranostics and biomarker discovery
Cancer has been constantly evolving and so is the research pertaining to cancer diagnosis
and therapeutic regimens. Early detection and specific therapeutics are the key features of …
and therapeutic regimens. Early detection and specific therapeutics are the key features of …
Characterization of core fucosylation via sequential enzymatic treatments of intact glycopeptides and mass spectrometry analysis
Core fucosylation of N-linked glycoproteins has been linked to the functions of glycoproteins
in physiological and pathological processes. However, quantitative characterization of core …
in physiological and pathological processes. However, quantitative characterization of core …
Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer
Hypoxia-inducible factors (HIFs) and NF-κB play essential roles in cancer cell growth and
metastasis by promoting angiogenesis. Heat shock protein 90 (Hsp90) serves as a regulator …
metastasis by promoting angiogenesis. Heat shock protein 90 (Hsp90) serves as a regulator …
FN1 encoding fibronectin as a pivotal signaling gene for therapeutic intervention against pancreatic cancer
The delayed diagnosis of pancreatic cancer has resulted in rising mortality rate and low
survival rate that can be circumvented using potent theranostics biomarkers. The treatment …
survival rate that can be circumvented using potent theranostics biomarkers. The treatment …
RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer
Gene expression microarrays have identified many tumor markers and therapeutic targets
for pancreatic ductal adenocarcinoma (PDAC). However, microarray profilings have limited …
for pancreatic ductal adenocarcinoma (PDAC). However, microarray profilings have limited …
Metabolomics based predictive classifier for early detection of pancreatic ductal adenocarcinoma
The availability of robust classification algorithms for the identification of high risk individuals
with resectable disease is critical to improving early detection strategies and ultimately …
with resectable disease is critical to improving early detection strategies and ultimately …
Metabolomic biomarkers of pancreatic cancer: a meta-analysis study
Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is
no blood test for early detection and diagnosis of this disease. Several research groups …
no blood test for early detection and diagnosis of this disease. Several research groups …
Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus
KM Moore, A Desai, B de Luxán Delgado… - …, 2020 - pmc.ncbi.nlm.nih.gov
Goals of investigation: The 5-year survival rate for pancreatic ductal adenocarcinoma
(PDAC) has remained at< 5% for decades because no effective therapies have been …
(PDAC) has remained at< 5% for decades because no effective therapies have been …