Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury
Essential metals are crucial for the maintenance of cell homeostasis. Among the 23
elements that have known physiological functions in humans, 12 are metals, including iron …
elements that have known physiological functions in humans, 12 are metals, including iron …
Fluorescent, MRI, and colorimetric chemical sensors for the first-row d-block metal ions
H Zhu, J Fan, B Wang, X Peng - Chemical Society Reviews, 2015 - pubs.rsc.org
Transition metals (d-blocks) are recognized as playing critical roles in biology, and they most
often act as cofactors in diverse enzymes; however, improper regulation of transition metal …
often act as cofactors in diverse enzymes; however, improper regulation of transition metal …
Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …
Copper in diseases and treatments, and copper‐based anticancer strategies
Copper is found in all living organisms and is a crucial trace element in redox chemistry,
growth and development. It is important for the function of several enzymes and proteins …
growth and development. It is important for the function of several enzymes and proteins …
Iron metabolism in oligodendrocytes and astrocytes, implications for myelination and remyelination
Iron is a key nutrient for normal central nervous system (CNS) development and function;
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS …
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS …
Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms
EE Battin, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
It is well known that oxidation caused by reactive oxygen species (ROS) is a major cause of
cellular damage and death and has been implicated in cancer, neurodegenerative, and …
cellular damage and death and has been implicated in cancer, neurodegenerative, and …
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
Oxidative stress and neurodegeneration: the involvement of iron
A Carocci, A Catalano, MS Sinicropi, G Genchi - Biometals, 2018 - Springer
Many evidences indicate that oxidative stress plays a significant role in a variety of human
disease states, including neurodegenerative diseases. Iron is an essential metal for almost …
disease states, including neurodegenerative diseases. Iron is an essential metal for almost …
Air Pollution, Oxidative Stress, and Alzheimer′ s Disease
Alzheimer′ s disease (AD) is the most common form of dementia affecting millions of
people worldwide and will continue to affect millions more with population aging on the rise …
people worldwide and will continue to affect millions more with population aging on the rise …