Role of indoleamine 2, 3-dioxygenase in health and disease
IDO1 (indoleamine 2, 3-dioxygenase 1) is a member of a unique class of mammalian haem
dioxygenases that catalyse the oxidative catabolism of the least-abundant essential amino …
dioxygenases that catalyse the oxidative catabolism of the least-abundant essential amino …
Pathogenetic mechanisms of T cell dysfunction in chronic HBV infection and related therapeutic approaches
A great effort of research has been devoted in the last few years to develo** new anti-HBV
therapies of finite duration that also provide effective sustained control of virus replication …
therapies of finite duration that also provide effective sustained control of virus replication …
[PDF][PDF] Immune tolerance in liver disease
IN Crispe - Hepatology, 2014 - Wiley Online Library
Liver tolerance is manifest as a bias toward immune unresponsiveness, both in the context
of a major histocompatibility complex–mismatched liver transplant and in the context of liver …
of a major histocompatibility complex–mismatched liver transplant and in the context of liver …
New insights into IDO biology in bacterial and viral infections
Initially, indoleamine-2, 3-dioxygenase (IDO) has been introduced as a bactericidal effector
mechanism and has been linked to T-cell immunosuppression and tolerance. In recent …
mechanism and has been linked to T-cell immunosuppression and tolerance. In recent …
Tryptophan catabolism in chronic viral infections: handling uninvited guests
L-Tryptophan (L-Trp) is an essential amino acid that possesses diverse metabolic,
neurological, and immunological roles spanning from the synthesis of proteins …
neurological, and immunological roles spanning from the synthesis of proteins …
Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers
Tryptophan (Trp) catabolism into immunosuppressive kynurenine (Kyn) by indoleamine 2, 3-
dioxygenase (IDO) was previously linked to Th17/Treg differentiation and immune activation …
dioxygenase (IDO) was previously linked to Th17/Treg differentiation and immune activation …
Hepatitis C virus induces MDSCs-like monocytes through TLR2/PI3K/AKT/STAT3 signaling
N Zhai, H Li, H Song, Y Yang, A Cui, T Li, J Niu… - PLoS …, 2017 - journals.plos.org
Background and Aims Recent studies reveal the accumulation of myeloid derived
suppressor cells (MDSCs) in human peripheral blood mononuclear cells (PBMCs) following …
suppressor cells (MDSCs) in human peripheral blood mononuclear cells (PBMCs) following …
Targeting regulatory T cells to improve vaccine immunogenicity in early life
Human newborns and infants are bombarded with multiple pathogens on leaving the sterile
intra-uterine environment, and yet have suboptimal innate immunity and limited …
intra-uterine environment, and yet have suboptimal innate immunity and limited …
Dendritic cells in liver transplantation immune response
X Du, M Li, C Huan, G Lv - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Dendritic cells (DCs) are the most powerful antigen presenting cells (APCs), they are
considered one of the key regulatory factors in the liver immune system. There is currently …
considered one of the key regulatory factors in the liver immune system. There is currently …
[HTML][HTML] A narrative review of the roles of indoleamine 2, 3-dioxygenase and tryptophan-2, 3-dioxygenase in liver diseases
Q Zhou, Y Shi, C Chen, F Wu… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Abstract Indoleamine 2, 3-dioxygenase (IDO) and tryptophan-2, 3-dioxygenase (TDO) are
induced by several immune factors, such as interferon-γ, and act as intracellular enzymes …
induced by several immune factors, such as interferon-γ, and act as intracellular enzymes …