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Metabolomics for investigating physiological and pathophysiological processes
DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …
The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva
A Amann, B de Lacy Costello, W Miekisch… - Journal of breath …, 2014 - iopscience.iop.org
Breath analysis is a young field of research with its roots in antiquity. Antoine Lavoisier
discovered carbon dioxide in exhaled breath during the period 1777–1783, Wilhelm (Vilém) …
discovered carbon dioxide in exhaled breath during the period 1777–1783, Wilhelm (Vilém) …
Advances in solid phase microextraction and perspective on future directions
Solid phase microextraction (SPME) is a versatile, nonex-haustive sample preparation tool
that has been demonstrated to be well-suited for facile and effective analysis of a broad …
that has been demonstrated to be well-suited for facile and effective analysis of a broad …
Gut microbiota profiling: metabolomics based approach to unravel compounds affecting human health
P Vernocchi, F Del Chierico, L Putignani - Frontiers in microbiology, 2016 - frontiersin.org
The gut microbiota is composed of a huge number of different bacteria, that produce a large
amount of compounds playing a key role in microbe selection and in the construction of a …
amount of compounds playing a key role in microbe selection and in the construction of a …
A review on human fecal metabolomics: Methods, applications and the human fecal metabolome database
Metabolomic analysis of human biospecimens had progressed quickly over the past
decade. Technological and methodological advances have led to the comprehensive …
decade. Technological and methodological advances have led to the comprehensive …
Stress and the microbiota–gut–brain axis in visceral pain: relevance to irritable bowel syndrome
Visceral pain is a global term used to describe pain originating from the internal organs of
the body, which affects a significant proportion of the population and is a common feature of …
the body, which affects a significant proportion of the population and is a common feature of …
Brain–gut microbiome interactions and functional bowel disorders
EA Mayer, T Savidge, RJ Shulman - Gastroenterology, 2014 - Elsevier
Alterations in the bidirectional interactions between the intestine and the nervous system
have important roles in the pathogenesis of irritable bowel syndrome (IBS). A body of largely …
have important roles in the pathogenesis of irritable bowel syndrome (IBS). A body of largely …
Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD
Objective Iron deficiency is a common complication in patients with IBD and oral iron therapy
is suggested to exacerbate IBD symptoms. We performed an open-labelled clinical trial to …
is suggested to exacerbate IBD symptoms. We performed an open-labelled clinical trial to …
Breathing new life into clinical testing and diagnostics: perspectives on volatile biomarkers from breath
Human breath offers several benefits for diagnostic applications, including simple,
noninvasive collection. Breath is a rich source of clinically-relevant biological information; …
noninvasive collection. Breath is a rich source of clinically-relevant biological information; …
Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe
It is well established that gut microbes and their metabolic products regulate host
metabolism. The interactions between the host and its gut microbiota are highly dynamic …
metabolism. The interactions between the host and its gut microbiota are highly dynamic …