Clozapine is an effective antipsychotic medication used for treatment‐resistant
schizophrenia. However, it is underutilized due to rigorous hematologic monitoring …

Objectives To compare the prevalence, regulations, and pharmacovigilance practices of
clozapine use in Eastern European countries (except Russia). Methods Questionnaires and …

Although uncommon, the risk of aggression and violence is greater in people with
schizophrenia than in the general population. Clozapine is the “gold standard” …

After the introduction of clozapine eight Finnish patients died after develo**
agranulocytosis. Clozapine was withdrawn from the market and only reintroduced with strict …

Background The literature has paid very little attention to pericarditis, pericardial effusion
and pancreatitis during clozapine treatment in children and adolescents. Methods Cases of …

Schizophrenia is a frequently debilitating and complex mental disorder affecting
approximately 1% of the global population, characterized by symptoms such as …

Abstract Background and Objectives Despite the evidence that no other antipsychotic is
effective as clozapine for the treatment of resistant schizophrenia, it is associated with …

Clozapine-induced myocarditis (CIM) is among the most important adverse events limiting
the use of clozapine as the most effective treatment for schizophrenia. CIM necessitates the …

Background Antipsychotic polypharmacy (APP) is frequent but evidence-based guidelines
on reducing APP to antipsychotic monotherapy (APM) are sparse. We aimed to …

Laboratories commonly provide norclozapine concentrations when a plasma clozapine level
is requested, but the appropriate use of this information for the treatment of individuals with …