The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are a
group of disorders involving severe, systemic, small-vessel vasculitis and are characterized …

Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative
colitis (UC), are intimately associated with inflammation and overproduction of reactive …

Background Management strategies and clinical outcomes vary substantially in patients
newly diagnosed with Crohn's disease. We evaluated the use of a putative prognostic …

CD8+ T cells are involved in the pathogenesis of inflammatory bowel disease (IBD), a
complex multifactorial chronic disease. Here, we present an overview of the current research …

Dysregulated host responses to infection can lead to organ dysfunction and sepsis, causing
millions of global deaths each year. To alleviate this burden, improved prognostication and …

Artificial intelligence (AI) has arrived and it will directly impact how we assess, monitor, and
manage inflammatory bowel disease (IBD). Advances in the machine learning …

Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Inflammatory bowel disease (IBD) is a complex and multifaceted disorder of the
gastrointestinal tract that is increasing in incidence worldwide and associated with …

Inflammatory bowel diseases (IBD) are chronic intermittent inflammatory disorders of the
gastrointestinal tract of unknown etiology but a clear genetic predisposition. Prompted by the …

Background and aims Treatment with tumor necrosis factor α (TNFα) antagonists in IBD
patients suffers from primary non-response rates of up to 40%. Biomarkers for early …