Thioredoxin‐interacting protein (TXNIP) was originally named vitamin D3 upregulated
protein‐1 (VDUP1) because of its ability to bind to thioredoxin (TRX) and inhibit TRX …

Thioredoxin-interacting protein (TXNIP), widely known as thioredoxin-binding protein 2
(TBP2), is a major binding mediator in the thioredoxin (TXN) antioxidant system, which …

Objective To examine the anti-inflammatory effects and potential mechanisms of polypeptide
from Moschus (PPM) in lipopolysaccharide (LPS)-induced THP-1 macrophages and BALB/c …

Alzheimer's Disease (AD) is a global chronic disease in adults with beta-amyloid (Aβ)
deposits and hyperphosphorylated tau protein as the pathologic characteristics. Although …

The development of new therapeutic approaches to diseases relies on the identification of
key molecular targets involved in amplifying disease processes. One such molecule is …

Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

Alzheimer's disease (AD) is the most common form of dementia characterized by
progressive memory loss and cognitive decline. Although neuroinflammation and oxidative …

Understanding the role of small, soluble aggregates of beta-amyloid (Aβ) and tau in
Alzheimer's disease (AD) is of great importance for the rational design of preventative …

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder
clinically characterized by cognitive impairment, abnormal behavior, and social deficits …

Although the exact etiology of Alzheimer's disease (AD) is poorly understood, experimental
and clinical evidences suggest the contribution of neuroinflammation in the pathogenesis of …