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Molecular mechanisms and physiological importance of circadian rhythms
A Patke, MW Young, S Axelrod - Nature reviews Molecular cell biology, 2020 - nature.com
To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …
behaviour and physiology, which include prominent behavioural states such as sleep–wake …
Circadian rhythms disrupted by light at night and mistimed food intake alter hormonal rhythms and metabolism
Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …
allowing 24-hour healthcare, commerce and production, and expanding social life around …
[HTML][HTML] Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer's disease
DS Whittaker, L Akhmetova, D Carlin, H Romero… - Cell metabolism, 2023 - cell.com
Circadian disruptions impact nearly all people with Alzheimer's disease (AD), emphasizing
both their potential role in pathology and the critical need to investigate the therapeutic …
both their potential role in pathology and the critical need to investigate the therapeutic …
Circadian rhythm as a therapeutic target
The circadian clock evolved in diverse organisms to integrate external environmental
changes and internal physiology. The clock endows the host with temporal precision and …
changes and internal physiology. The clock endows the host with temporal precision and …
Magnetic field effects in biology from the perspective of the radical pair mechanism
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …
biological systems. However, the underlying mechanisms behind these phenomena remain …
Time-restricted eating to prevent and manage chronic metabolic diseases
Molecular clocks are present in almost every cell to anticipate daily recurring and
predictable changes, such as rhythmic nutrient availability, and to adapt cellular functions …
predictable changes, such as rhythmic nutrient availability, and to adapt cellular functions …
Transcriptional architecture of the mammalian circadian clock
JS Takahashi - Nature Reviews Genetics, 2017 - nature.com
Circadian clocks are endogenous oscillators that control 24-hour physiological and
behavioural processes in organisms. These cell-autonomous clocks are composed of a …
behavioural processes in organisms. These cell-autonomous clocks are composed of a …
Circadian clock genes and the transcriptional architecture of the clock mechanism
KH Cox, JS Takahashi - Journal of molecular endocrinology, 2019 - jme.bioscientifica.com
The mammalian circadian clock has evolved as an adaptation to the 24-h light/darkness
cycle on earth. Maintaining cellular activities in synchrony with the activities of the organism …
cycle on earth. Maintaining cellular activities in synchrony with the activities of the organism …
Circadian physiology of metabolism
S Panda - Science, 2016 - science.org
A majority of mammalian genes exhibit daily fluctuations in expression levels, making
circadian expression rhythms the largest known regulatory network in normal physiology …
circadian expression rhythms the largest known regulatory network in normal physiology …
The emerging link between cancer, metabolism, and circadian rhythms
S Masri, P Sassone-Corsi - Nature medicine, 2018 - nature.com
The circadian clock is a complex cellular mechanism that, through the control of diverse
metabolic and gene expression pathways, governs a large array of cyclic physiological …
metabolic and gene expression pathways, governs a large array of cyclic physiological …