Computational prediction of drug–target interactions (DTIs) has become an essential task in
the drug discovery process. It narrows down the search space for interactions by suggesting …

Network medicine is an emerging area of research dealing with molecular and genetic
interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale …

Resources that capture information about signaling pathways from the literature are
essential for the experimental design and analysis of many biological studies. Multiple …

Genome-wide association (GWA) studies have typically focused on the analysis of single
markers, which often lacks the power to uncover the relatively small effect sizes conferred by …

Protein interactions form a complex dynamic molecular system that shapes cell phenotype
and function; in this regard, network analysis is a powerful tool for studying the dynamics of …

The pace, by which scientific knowledge is being produced and shared today, was never
been so fast in the past. Different areas of science are getting closer to each other to give …

Aristolochic acid nephropathy (AAN) is characterized by acute proximal tubule necrosis and
immune cell infiltration, contributing to the global burden of chronic kidney disease and …

Multi-omics integration is key to fully understand complex biological processes in an holistic
manner. Furthermore, multi-omics combined with new longitudinal experimental design can …

The current therapeutic arsenal against viral infections remains limited, with often poor
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …

Empowered by the advancement of high-throughput bio technologies, recent research on
body-fluid proteomes has led to the discoveries of numerous novel disease biomarkers and …