Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …

As long-lived parasites, helminths depend upon immunomodulation of their hosts for
survival. The release of excretory-secretory (ES) products, including proteins, lipids and …

The major soil-transmitted helminths that infect humans are the roundworms, whipworms
and hookworms. Soil-transmitted helminth infections rank among the most important …

Parasitic helminths have coevolved with humans over millennia, intricately refining and
develo** an array of mechanisms to suppress or skew the host's immune system, thereby …

Parasitic helminths secrete and excrete a vast array of molecules known to help skew or
suppress the host's immune response, thereby establishing a niche for sustained parasite …

Introduction Helminths are parasitic worms that infect millions of people worldwide and
secrete a variety of excretory-secretory products (ESPs), including proteins, peptides, and …

Experimental and epidemiological evidence shows that parasites, particularly helminths,
play a central role in balancing the host immunity. It was demonstrated that parasites can …

Inflammatory bowel disease (IBD) is associated with a dysregulated mucosal immune
response in the gastrointestinal tract. The number of patients with IBD has increased …

Introduction Soil-transmitted helminths infect billions of people, livestock and companion
animals worldwide, and chronic infections with these nematodes represent a major health …

Helminth-derived proteins have immunomodulatory properties, influencing the host's
immune response as an adaptive strategy for helminth survival. Helminth-derived proteins …