E-cadherin is a transmembrane glycoprotein which connects epithelial cells together at
adherens junctions. In normal cells, E-cadherin exerts its tumour suppressing role mainly by …

MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression
post-transcriptionally. As a consequence of their function towards mRNA, miRNAs are …

Cancer is a complex multistep process involving genetic and epigenetic changes that
eventually result in the activation of oncogenic pathways and/or inactivation of tumor …

The development and progression of melanoma have been attributed to independent or
combined genetic and epigenetic events. There has been remarkable progress in …

Metastasis is the leading cause of cancer-associated death in most tumor types. Metastatic
dissemination of cancer cells from the primary tumor is believed to be initiated by the …

Yin Yang 1 (YY1), a dual function transcription factor, is known to regulate transcriptional
activation and repression of many genes associated with multiple cellular processes …

Ferroptosis is a recently recognized form of regulated cell death driven by lipid‐based
reactive oxygen species (ROS) accumulation. However, the molecular mechanisms of …

Melanoma is a life-threatening malignancy with poor prognosis and a relatively high burden
of mortality in advanced stages. The efficacy of current available therapeutic strategies is …

The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …

The epithelial–mesenchymal transition (EMT) is thought to be at the root of invasive and
metastatic cancer cell spreading. E-cadherin is an important player in this process, which …