Host and viral determinants of influenza A virus species specificity

JS Long, B Mistry, SM Haslam… - Nature Reviews …, 2019 - nature.com
Influenza A viruses cause pandemics when they cross between species and an
antigenically novel virus acquires the ability to infect and transmit between these new hosts …

A global perspective on H9N2 avian influenza virus

TP Peacock, J James, JE Sealy, M Iqbal - Viruses, 2019 - mdpi.com
H9N2 avian influenza viruses have become globally widespread in poultry over the last two
decades and represent a genuine threat both to the global poultry industry but also humans …

Rapid evolution of A (H5N1) influenza viruses after intercontinental spread to North America

A Kandeil, C Patton, JC Jones, T Jeevan… - Nature …, 2023 - nature.com
Highly pathogenic avian influenza A (H5N1) viruses of clade 2.3. 4.4 b underwent an
explosive geographic expansion in 2021 among wild birds and domestic poultry across …

Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance

B Dadonaite, JJ Ahn, JT Ort, J Yu, C Furey… - PLoS …, 2024 - journals.plos.org
H5 influenza is considered a potential pandemic threat. Recently, H5 viruses belonging to
clade 2.3. 4.4 b have caused large outbreaks in avian and multiple nonhuman mammalian …

Fusion of enveloped viruses in endosomes

JM White, GR Whittaker - Traffic, 2016 - Wiley Online Library
Ari Helenius launched the field of enveloped virus fusion in endosomes with a seminal
paper in the Journal of Cell Biology in 1980. In the intervening years, a great deal has been …

An overview of influenza A virus genes, protein functions, and replication cycle highlighting important updates

RP Chauhan, ML Gordon - Virus Genes, 2022 - Springer
The recent research findings on influenza A virus (IAV) genome biology prompted us to
present a comprehensive overview of IAV genes, protein functions, and replication cycle …

Influenza hemagglutinin protein stability, activation, and pandemic risk

CJ Russell, M Hu, FA Okda - Trends in microbiology, 2018 - cell.com
For decades, hemagglutinin (HA) protein structure and its refolding mechanism have served
as a paradigm for understanding protein-mediated membrane fusion. HA trimers are in a …

Hemagglutinin stability and its impact on influenza A virus infectivity, pathogenicity, and transmissibility in avians, mice, swine, seals, ferrets, and humans

CJ Russell - Viruses, 2021 - mdpi.com
Genetically diverse influenza A viruses (IAVs) circulate in wild aquatic birds. From this
reservoir, IAVs sporadically cause outbreaks, epidemics, and pandemics in wild and …

Increased public health threat of avian-origin H3N2 influenza virus caused by its evolution in dogs

M Chen, Y Lyu, F Wu, Y Zhang, H Li, R Wang, Y Liu… - Elife, 2023 - elifesciences.org
Influenza A viruses in animal reservoirs repeatedly cross species barriers to infect humans.
Dogs are the closest companion animals to humans, but the role of dogs in the ecology of …

Novel Epidemiologic Features of High Pathogenicity Avian Influenza Virus A H5N1 2.3. 3.4 b Panzootic: A Review

C Sacristán, AC Ewbank… - Transboundary and …, 2024 - Wiley Online Library
Avian influenza is one of the most devastating avian diseases. The current high
pathogenicity avian influenza (HPAI) A virus H5N1 clade 2.3. 4.4 b epizootic began in the …