Technology of deep brain stimulation: current status and future directions
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …
Towards network-guided neuromodulation for epilepsy
Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …
research to identify critical nodes within dynamic epileptic networks with the aim to target …
Chronic adaptive deep brain stimulation versus conventional stimulation in Parkinson's disease: a blinded randomized feasibility trial
Deep brain stimulation (DBS) is a widely used therapy for Parkinson's disease (PD) but
lacks dynamic responsiveness to changing clinical and neural states. Feedback control …
lacks dynamic responsiveness to changing clinical and neural states. Feedback control …
Deep brain stimulation of the thalamus restores signatures of consciousness in a nonhuman primate model
Loss of consciousness is associated with the disruption of long-range thalamocortical and
corticocortical brain communication. We tested the hypothesis that deep brain stimulation …
corticocortical brain communication. We tested the hypothesis that deep brain stimulation …
Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease
Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …
Neural signatures of hyperdirect pathway activity in Parkinson's disease
Parkinson's disease (PD) is characterised by the emergence of beta frequency oscillatory
synchronisation across the cortico-basal-ganglia circuit. The relationship between the …
synchronisation across the cortico-basal-ganglia circuit. The relationship between the …
[HTML][HTML] Lead-DBS v3. 0: Map** deep brain stimulation effects to local anatomy and global networks
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …
Deep brain stimulation targets in epilepsy: systematic review and meta‐analysis of anterior and centromedian thalamic nuclei and hippocampus
Deep brain stimulation (DBS) is a neuromodulatory treatment used in patients with drug‐
resistant epilepsy (DRE). The primary goal of this systematic review and meta‐analysis is to …
resistant epilepsy (DRE). The primary goal of this systematic review and meta‐analysis is to …
Dynamic coupling of whole-brain neuronal and neurotransmitter systems
Remarkable progress has come from whole-brain models linking anatomy and function.
Paradoxically, it is not clear how a neuronal dynamical system running in the fixed human …
Paradoxically, it is not clear how a neuronal dynamical system running in the fixed human …
A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder
Multiple surgical targets for treating obsessive-compulsive disorder with deep brain
stimulation (DBS) have been proposed. However, different targets may modulate the same …
stimulation (DBS) have been proposed. However, different targets may modulate the same …