From migraine genes to mechanisms

EA Tolner, T Houben, GM Terwindt, B de Vries… - Pain, 2015‏ - journals.lww.com
Migraine is a common multifactorial episodic brain disorder with strong genetic basis.
Monogenic subtypes include rare familial hemiplegic migraine, cerebral autosomal …

Diamine Oxidase rs10156191 and rs2052129 Variants Are Associated With the Risk for Migraine

E García‐Martín, C Martínez, M Serrador… - … : The Journal of …, 2015‏ - Wiley Online Library
Background Histamine has been implicated in the pathogenesis of migraine. We
investigated the possible association between functional single nucleotide polymorphisms …

The omics in migraine

L Lionetto, G Gentile, E Bellei, M Capi, D Sabato… - The Journal of …, 2013‏ - Springer
The term omics consist of three main areas of molecular biology, such as genomics,
proteomics and metabolomics. The omics synergism recognise migraine as an ideal study …

Population-based approaches to genetics of migraine

DI Chasman, M Schuerks, T Kurth - Cephalalgia, 2016‏ - journals.sagepub.com
Background While the most accurate diagnosis of migraine typically requires a clinical
interview guided by strict diagnostic criteria, an alternative approach that ascertains …

Replication of Migraine GWAS Susceptibility Loci in C hinese H an Population

X Fan, J Wang, W Fan, L Chen, B Gui… - … : The Journal of …, 2014‏ - Wiley Online Library
Background Recent genome‐wide association studies (GWAS) have identified 3 genetic
variants that are strongly associated with migraine in E uropeans. The effect of these risk …

Replication study of previous migraine genome-wide association study findings in a Spanish sample of migraine with aura

C Sintas, J Fernández-Morales, M Vila-Pueyo… - …, 2015‏ - journals.sagepub.com
Background Migraine is a common disabling condition that affects approximately 15% of the
population. Several genome-wide association studies have attempted to identify …

Implications for the migraine SNP rs1835740 in a Swedish cluster headache population

C Ran, C Fourier, M Zinnegger, A Steinberg… - The Journal of …, 2018‏ - Springer
Background Cluster headache is a severe headache disorder with unknown aetiology. The
pathophysiology and symptoms present certain common features with migraine. Specifically …

Multilocus analysis of hormonal, neurotransmitter, inflammatory pathways and genome‐wide associated variants in migraine susceptibility

J Ghosh, S Pradhan, B Mittal - European journal of neurology, 2014‏ - Wiley Online Library
Background and purpose Migraine pathophysiology involves a complex interplay of
processes wherein the hormonal, neurotransmitter and inflammatory pathways interact to …

SLC1A2 rs3794087 variant and risk for migraine

E García-Martín, C Martínez, M Serrador… - Journal of the …, 2014‏ - Elsevier
Background/objectives Glutamate has been implicated in the pathogenesis of migraine. We
investigated the possible association between the polymorphism rs3794087 in the SLC1A2 …

Genetic bases of the nutritional approach to migraine

ML De Marchis, F Guadagni, E Silvestris… - Critical reviews in …, 2019‏ - Taylor & Francis
Migraine is a common multifactorial and polygenic neurological disabling disorder
characterized by a genetic background and associated to environmental, hormonal and food …