Schizophrenia—an overview

RA McCutcheon, TR Marques, OD Howes - JAMA psychiatry, 2020 - jamanetwork.com
Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …

Neurocognitive functioning in individuals at clinical high risk for psychosis: a systematic review and meta-analysis

A Catalan, GS De Pablo, C Aymerich, S Damiani… - JAMA …, 2021 - jamanetwork.com
Importance Neurocognitive functioning is a potential biomarker to advance detection,
prognosis, and preventive care for individuals at clinical high risk for psychosis (CHR-P) …

Effectiveness, core elements, and moderators of response of cognitive remediation for schizophrenia: a systematic review and meta-analysis of randomized clinical …

A Vita, S Barlati, A Ceraso, G Nibbio, C Ariu… - JAMA …, 2021 - jamanetwork.com
Importance Cognitive impairment is a core feature of schizophrenia, with negative
consequences on functional outcomes. Although cognitive remediation (CR) is effective and …

Cognitive deficits in psychotic disorders: a lifespan perspective

JM Sheffield, NR Karcher, DM Barch - Neuropsychology review, 2018 - Springer
Individuals with disorders that include psychotic symptoms (ie psychotic disorders)
experience broad cognitive impairments in the chronic state, indicating a dimension of …

European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia

A Vita, W Gaebel, A Mucci, G Sachs, A Erfurth… - European …, 2022 - cambridge.org
Background Impairment in a wide range of cognitive abilities has been consistently reported
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …

Deconstructing vulnerability for psychosis: meta-analysis of environmental risk factors for psychosis in subjects at ultra high-risk

P Fusar-Poli, M Tantardini, S De Simone… - European …, 2017 - cambridge.org
BackgroundSubjects at ultra high-risk (UHR) for psychosis have an enhanced vulnerability
to develop the disorder but the risk factors accounting for this accrued risk are undetermined …

The psychosis high-risk state: a comprehensive state-of-the-art review

P Fusar-Poli, S Borgwardt, A Bechdolf… - JAMA …, 2013 - jamanetwork.com
Context During the past 2 decades, a major transition in the clinical characterization of
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …

Exercise improves clinical symptoms, quality of life, global functioning, and depression in schizophrenia: a systematic review and meta-analysis

M Dauwan, MJH Begemann, SM Heringa… - Schizophrenia …, 2016 - academic.oup.com
Background: Physical exercise may be valuable for patients with schizophrenia spectrum
disorders as it may have beneficial effect on clinical symptoms, quality of life and cognition …

Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk

P Fusar-Poli, I Bonoldi, AR Yung… - Archives of general …, 2012 - jamanetwork.com
Context A substantial proportion of people at clinical high risk of psychosis will develop a
psychotic disorder over time. However, the risk of transition to psychosis varies between …

The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological …

M Pruessner, AE Cullen, M Aas, EF Walker - … & Biobehavioral Reviews, 2017 - Elsevier
Over the past decade, our understanding of the role of stress in serious mental illness has
become more sophisticated. In this paper, we revisit the neural diathesis-stress model of …