The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …

Cancer is a devastating disease and is the second leading cause of death worldwide.
Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for …

Cancer is a multistep process resulting in uncontrolled cell division. It results from aberrant
signaling pathways that lead to uninhibited cell division and growth. Various recent …

Drug resistance is the main obstacle to achieving a cure in many cancer patients. Reactive
oxygen species (ROS) are master regulators of cancer development that act through …

Sulfasalazine (SSZ) is an anti-inflammatory drug that has been demonstrated to induce
apoptosis and tumor regression through inhibition of plasma membrane cystine transporter …

Inverse association between dietary intake of cruciferous vegetables and cancer risk
observed in population-based case-control studies is partly attributable to structurally simple …

Bladder cancer (BC) is a representative of urological cancer with a high recurrence and
metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint …

Cisplatin (cis-diamminedichloroplatinum II, CIS) is a potent and widely used
chemotherapeutic agent to treat various malignancies, but its therapeutic use is limited …

Natural isothiocyanates (ITCs) are phytochemicals abundant in cruciferous vegetables with
the general structure, R–Ndouble bondCdouble bondS. They are bioactive organosulfur …

The success of cancer therapy is often compromised by the narrow therapeutic index of
many anticancer drugs and the occurrence of drug resistance. The association of anticancer …