Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

While knowledge of the composition and mode of action of bee and wasp venoms dates
back 50 years, the therapeutic value of these toxins remains relatively unexploded. The …

Fluid and HCO3− secretion is a vital function of all epithelia and is required for the survival of
the tissue. Aberrant fluid and HCO3− secretion is associated with many epithelial diseases …

Human and mouse genomes contain a similar number of CpG islands (CGIs), which are
discrete CpG-rich DNA sequences associated with transcription start sites. In both …

In the nervous system, NMDA receptors (NMDARs) participate in neurotransmission and
modulate the viability of neurons. In contrast, little is known about the role of NMDARs in …

A variety of ion channels, including members of all major ion channel families, have been
shown to be regulated by changes in the level of membrane cholesterol and partition into …

Hereditary erythrocyte membrane disorders are caused by mutations in genes encoding
various transmembrane or cytoskeletal proteins of red blood cells. The main consequences …

The Ca2+-activated K+ channel KCa3. 1 regulates membrane potential and calcium
signaling in erythrocytes, activated T and B cells, macrophages, microglia, vascular …

When red blood cells (RBCs) pass constrictions or small capillaries they need to pass
apertures falling well below their own cross section size. We used different means of …

In close interaction with photoreceptors, the retinal pigment epithelium (RPE) plays an
essential role for visual function. The analysis of RPE functions, specifically ion channel …