Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …

Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …

Alzheimer's disease is a chronic and progressive brain neurodegenerative disease affecting
over 30 million people globally. Currently, no effective treatment is available due to multiple …

Abstract Alzheimer's disease (AD), one of the most common neurodegenerative diseases
worldwide, has a devastating personal, familial, and societal impact. In spite of profound …

Based on a multitarget strategy, a series of novel tacrine–pyrimidone hybrids were identified
for the potential treatment of Alzheimer's disease (AD). Biological evaluation results …

Pyridinones have been adopted as an important block in medicinal chemistry that could
serve as hydrogen bond donors and acceptors. With the help of feasible synthesis routes via …

Selective elimination of senescent cells (senolysis) has become a promising therapeutic
strategy for the management of chronic renal failure (CRF), but the senolytic molecular …

In the last few years, Monoamine oxidase (MAO) have emerged as a target for the treatment
of many neurodegenerative diseases including anxiety, depression, Alzheimer's, and …

Alzheimer's disease (AD) is a major progressive and perplexing cortical degenerative
disease of the brain in the elderly. It contributes to a significant socioeconomic burden on …

Iron is an essential mineral that serves as a prosthetic group for a variety of proteins involved
in vital cellular processes. The iron economy within humans is highly conserved in that there …