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Snake venomics: fundamentals, recent updates, and a look to the next decade
CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
Antivenom preclinical efficacy testing against Asian snakes and their availability in Asia: A systematic review
Background Cross-neutralizing strategy has been applied to improve access to antivenoms,
a key to reducing mortality and disability of snakebite envenoming. However, preclinical …
a key to reducing mortality and disability of snakebite envenoming. However, preclinical …
High-throughput venomics
J Slagboom, RJE Derks, R Sadighi… - Journal of Proteome …, 2023 - ACS Publications
In this study, we present high-throughput (HT) venomics, a novel analytical strategy capable
of performing a full proteomic analysis of a snake venom within 3 days. This methodology …
of performing a full proteomic analysis of a snake venom within 3 days. This methodology …
[HTML][HTML] Analytical strategies in venomics
Snakebite envenoming is a major issue in certain develo** parts of the world, with tens of
thousands of deaths and a multitude of lingering permanent medical conditions on a yearly …
thousands of deaths and a multitude of lingering permanent medical conditions on a yearly …
[HTML][HTML] Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance
Snakebite envenoming is a neglected tropical disease that may claim over 100,000 human
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …
lives annually worldwide. Snakebite occurs as the result of an interaction between a human …
[HTML][HTML] Proteomics and antivenom immunoprofiling of Russell's viper (Daboia siamensis) venoms from Thailand and Indonesia
Background The Eastern Russell's viper, Daboia siamensis, is a WHO Category 1 medically
important venomous snake. It has a wide but disjunct distribution in Southeast Asia. The …
important venomous snake. It has a wide but disjunct distribution in Southeast Asia. The …
[HTML][HTML] Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell's viper (Daboia russelii) venoms
Abstract Background: The western Russell's viper (Daboia russelii) is widely distributed in
South Asia, and geographical venom variation is anticipated among distant populations …
South Asia, and geographical venom variation is anticipated among distant populations …
Proteomic insights into short neurotoxin-driven, highly neurotoxic venom of Philippine cobra (Naja philippinensis) and toxicity correlation of cobra envenomation in …
Abstract The Philippine cobra, Naja philippinensis, is a WHO Category 1 venomous snake of
medical importance responsible for fatal envenomation in the northern Philippines. To …
medical importance responsible for fatal envenomation in the northern Philippines. To …
Venom composition of Trimeresurus albolabris, T. insularis, T. puniceus and T. purpureomaculatus from Indonesia
Background: Several studies have been published on the characterization of Trimeresurus
venoms. However, there is still limited information concerning the venom composition of …
venoms. However, there is still limited information concerning the venom composition of …
Clinical implications of differential procoagulant toxicity of the palearctic viperid genus Macrovipera, and the relative neutralization efficacy of antivenoms and enzyme …
Species within the viperid genus Macrovipera are some of the most dangerous snakes in the
Eurasian region, injecting copious amounts of potent venom. Despite their medical …
Eurasian region, injecting copious amounts of potent venom. Despite their medical …