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Nonnegative matrix factorization: an analytical and interpretive tool in computational biology
K Devarajan - PLoS computational biology, 2008 - journals.plos.org
In the last decade, advances in high-throughput technologies such as DNA microarrays
have made it possible to simultaneously measure the expression levels of tens of thousands …
have made it possible to simultaneously measure the expression levels of tens of thousands …
Making sense of cancer genomic data
High-throughput tools for nucleic acid characterization now provide the means to conduct
comprehensive analyses of all somatic alterations in the cancer genomes. Both large-scale …
comprehensive analyses of all somatic alterations in the cancer genomes. Both large-scale …
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
Y Jiang, A Sun, Y Zhao, W Ying, H Sun, X Yang, B ** …
Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer
MD Burstein, A Tsimelzon, GM Poage… - Clinical Cancer …, 2015 - aacrjournals.org
Purpose: Genomic profiling studies suggest that triple-negative breast cancer (TNBC) is a
heterogeneous disease. In this study, we sought to define TNBC subtypes and identify …
heterogeneous disease. In this study, we sought to define TNBC subtypes and identify …
Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors
A Daemen, D Peterson, N Sahu, R McCord… - Proceedings of the …, 2015 - pnas.org
Although targeting cancer metabolism is a promising therapeutic strategy, clinical success
will depend on an accurate diagnostic identification of tumor subtypes with specific …
will depend on an accurate diagnostic identification of tumor subtypes with specific …
Deep learning approach based on dimensionality reduction for designing electromagnetic nanostructures
In this paper, we demonstrate a computationally efficient new approach based on deep
learning (DL) techniques for analysis, design and optimization of electromagnetic (EM) …
learning (DL) techniques for analysis, design and optimization of electromagnetic (EM) …
[書籍][B] Nonnegative matrix and tensor factorizations: applications to exploratory multi-way data analysis and blind source separation
This book provides a broad survey of models and efficient algorithms for Nonnegative Matrix
Factorization (NMF). This includes NMF's various extensions and modifications, especially …
Factorization (NMF). This includes NMF's various extensions and modifications, especially …
Non-negative matrix factorization with sparseness constraints
PO Hoyer - Journal of machine learning research, 2004 - jmlr.org
Non-negative matrix factorization (NMF) is a recently developed technique for finding parts-
based, linear representations of non-negative data. Although it has successfully been …
based, linear representations of non-negative data. Although it has successfully been …
Metagenes and molecular pattern discovery using matrix factorization
We describe here the use of nonnegative matrix factorization (NMF), an algorithm based on
decomposition by parts that can reduce the dimension of expression data from thousands of …
decomposition by parts that can reduce the dimension of expression data from thousands of …
A flexible R package for nonnegative matrix factorization
R Gaujoux, C Seoighe - BMC bioinformatics, 2010 - Springer
Abstract Background Nonnegative Matrix Factorization (NMF) is an unsupervised learning
technique that has been applied successfully in several fields, including signal processing …
technique that has been applied successfully in several fields, including signal processing …