Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications

G Jubete, R Puig de la Bellacasa, R Estrada-Tejedor… - Molecules, 2019 - mdpi.com
Pyrido [2, 3-d] pyrimidines (1) are a type of privileged heterocyclic scaffolds capable of
providing ligands for several receptors in the body. Among such structures, our group and …

Photo‐Facilitated Detection and Sequencing of 5‐Formylcytidine RNA

XY **, ZR Huang, LJ **e, L Liu, DL Han… - Angewandte …, 2022 - Wiley Online Library
Formylcytidine (f5C) is one of the epigenetic nucleotides in tRNA. Despite the evident
importance of f5C in gene expression regulation, little is known about its exact amount and …

Synthesis of new pyrido[2,3-d]pyrimidin-5-one, pyrido[2,3-d]pyrimidin-7-one, and pyrimidino[4,5-d][1,3]oxazine derivatives from 5-acetyl-4-aminopyrimidines

AV Komkov, MA Kozlov, AS Dmitrenok… - Chemistry of …, 2021 - Springer
Methods were developed for the synthesis of new pyrido [2, 3-d] pyrimidine and pyrimidino
[4, 5-d][1, 3] oxazine derivatives. When heated under reflux with MeONa in BuOH, 5-acetyl-4 …

Synthesis of new pyrido[2,3-d]pyrimidin-5-ones and pyrido[2,3-d]pyrimidin-7-ones functionalized at position 4 from 5-acetyl-6-amino-4-methylsulfanyl-2 …

AV Komkov, MA Kozlov, DI Nasyrova… - Chemistry of …, 2022 - Springer
Methods were developed for the synthesis of new pyrido [2, 3-d] pyrimidin-5-ones and
pyrido [2, 3-d] pyrimidin-7-ones from 5-acetyl-N-acyl-6-amino-4-methylsulfanyl-2 …

[HTML][HTML] Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido [2, 3-d] pyrimidine as inhibitors of protein kinase CK2

AN Zinchenko, LV Muzychka, OB Smolii… - Biopolymers and …, 2017 - biopolymers.org.ua
Aim. A search for human protein kinase CK2 inhibitors in a series of new amino-substituted
pyrido [2, 3-d] pyrimidine derivatives. Methods. Organic synthesis, analytical and spectral …

A Photo-triggered Wittig-Cyclization for Detecting and Sequencing 5-Formylcytidine in RNA

L Cheng, XY **, ZR Huang, DL Han, LJ **e, L Liu - 2022 - chemrxiv.org
The simultaneous detection of a specific post-transcriptional modification that decorates the
natural RNA can provide comprehensive information to better understand cellular and …

СИНТЕЗ НОВЫХ ПИРИДО[2,3-d]ПИРИМИДИН-5-ОНОВ И ПИРИДО[2,3-d]ПИРИМИДИН-7-ОНОВ С ФУНКЦИОНАЛЬНЫМИ ГРУППАМИ В ПОЛОЖЕНИИ 4 ИЗ …

В Александр, МА Козлов, ДИ Насырова… - Chemistry of …, 2022 - 5.179.29.131
Разработаны методы синтеза новых пиридо [2, 3-d] пиримидин-5-онов и пиридо [2, 3-d]
пиримидин-7-онов из 6-амино-5-ацетил-N-ацил-4-метилсульфанил-2 …

Bicyclic 6-6 Systems: Three Heteroatoms 1: 2

W Loughlin, A Boufridi - 2022 - research-repository.griffith.edu.au
The chemistry of 6-6 fused heterocycles containing three heteroatoms arranged 1: 2 with no
heteroatoms occupying the bridgehead position is reviewed and updated for the period …

[HTML][HTML] Піридо [2, 3-d] піримідин-7-они: синтез та біологічні властивості

HM Zinchenko, LV Muzychka… - Journal of Organic and …, 2019 - ophcj.nuph.edu.ua
В огляді узагальнено та систематизовано дані останніх двадцяти років щодо методів
одержання та біологічних властивостей піридо [2, 3-d] піримідин-7-онів–перспективних …

Изучение взаимодействия 4, 6-дихлорпиримидин-5-карбальгегида с эфирами глицина

ГМ Зінченко, ЛВ Музичка, ІІ Білецький… - Журнал органічної та …, 2018 - elibrary.ru
Цель работы-исследование реакции 4, 6-дихлорпиримидин-5-карбальдегида с метил-и
трет-бутилглицинатами с целью выявления особенностей взаимодействия в …