Recent researches in triazole compounds as medicinal drugs
C -H. Zhou, Y Wang - Current medicinal chemistry, 2012 - benthamdirect.com
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …
ring are readily able to bind with a variety of enzymes and receptors in biological system via …
Pharmacological significance of triazole scaffold
The triazole nucleus is one of the most important and well known heterocycles which is a
common and integral feature of a variety of natural products and medicinal agents. Triazole …
common and integral feature of a variety of natural products and medicinal agents. Triazole …
Recent advances bioactive 1, 2, 4-triazole-3-thiones
ŞG Küçükgüzel, P Çıkla-Süzgün - European journal of medicinal chemistry, 2015 - Elsevier
Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …
atoms and three nitrogen atoms. These structures have been interest in the development of …
Recent developments on triazole nucleus in anticonvulsant compounds: a review
MX Song, XQ Deng - Journal of enzyme inhibition and medicinal …, 2018 - Taylor & Francis
Epilepsy is one of the common diseases seriously threatening life and health of human.
More than 50 million people are suffering from this condition and anticonvulsant agents are …
More than 50 million people are suffering from this condition and anticonvulsant agents are …
Synthesis of novel 1, 3, 4-oxadiazole derivatives and their biological properties
A Husain, M Ajmal - Acta pharmaceutica, 2009 - hrcak.srce.hr
Sažetak A novel series of 2-[3-(4-bromophenyl) propan-3-one]-5-(substituted phenyl)-1, 3, 4-
oxadiazoles (4a-n) have been synthesized from 3-(4-bromobenzoyl) propionic acid (3) with …
oxadiazoles (4a-n) have been synthesized from 3-(4-bromobenzoyl) propionic acid (3) with …
Exploration of nonlinear optical properties of 4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-phenylpropanamide based derivatives: experimental and DFT approach
Triazoles, nitrogen-containing heterocycles, have gained attention for their applications in
medicinal chemistry, drug discovery, agrochemicals, and material sciences. In the current …
medicinal chemistry, drug discovery, agrochemicals, and material sciences. In the current …
Chemistry and biology of indoles and indazoles: a mini-review
NA Shafakat Ali, B Ahmad Dar… - Mini reviews in …, 2013 - benthamdirect.com
The present review article is related with the method of preparation, importance and
medicinal application of indole and indazoles. The studies of heterocycles is an evergreen …
medicinal application of indole and indazoles. The studies of heterocycles is an evergreen …
A comprehensive review of N-heterocycles as cytotoxic agents
Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …
The importance of triazole scaffold in the development of anticonvulsant agents
Epilepsy is one of the most important neurological disorders with high prevalence
worldwide. Many epileptic patients are not completely treated with available drugs and need …
worldwide. Many epileptic patients are not completely treated with available drugs and need …
Synthesis, characterization and preliminary anticonvulsant evaluation of some 4-alkyl-1, 2, 4-triazoles
T Plech, JJ Luszczki, M Wujec, J Flieger… - European Journal of …, 2013 - Elsevier
Designed and synthesized 4-alkyl-1, 2, 4-triazole-3-thione derivatives showed significant
anticonvulsant activity, determined in the maximal electroshock-induced seizure (MES) test …
anticonvulsant activity, determined in the maximal electroshock-induced seizure (MES) test …