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T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …
Genomic investigations of unexplained acute hepatitis in children
Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis
in children have been reported worldwide, including 278 cases in the UK. Here we report an …
in children have been reported worldwide, including 278 cases in the UK. Here we report an …
Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …
Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults
Human infection challenge permits in-depth, early, and pre-symptomatic characterization of
the immune response, enabling the identification of factors that are important for viral …
the immune response, enabling the identification of factors that are important for viral …
In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms
S Cankat, MU Demael, L Swadling - Cellular & molecular immunology, 2024 - nature.com
Members of the coronaviridae family are endemic to human populations and have caused
several epidemics and pandemics in recent history. In this review, we will discuss the …
several epidemics and pandemics in recent history. In this review, we will discuss the …
Silent battles: immune responses in asymptomatic SARS-CoV-2 infection
N Le Bert, T Samandari - Cellular & Molecular Immunology, 2024 - nature.com
SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …
Defending against SARS-CoV-2: The T cell perspective
P Almendro-Vázquez, R Laguna-Goya… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …
Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …
CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment
M Kar, KEE Johnson, A Vanderheiden, EJ Elrod… - Science …, 2024 - science.org
SARS-CoV-2 infection induces the generation of virus-specific CD4+ and CD8+ effector and
memory T cells. However, the contribution of T cells in controlling SARS-CoV-2 during …
memory T cells. However, the contribution of T cells in controlling SARS-CoV-2 during …