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[HTML][HTML] Low-dose metformin targets the lysosomal AMPK pathway through PEN2
Metformin, the most prescribed antidiabetic medicine, has shown other benefits such as anti-
ageing and anticancer effects,,–. For clinical doses of metformin, AMP-activated protein …
ageing and anticancer effects,,–. For clinical doses of metformin, AMP-activated protein …
Effects of dielectric barrier discharge (DBD) cold plasma treatment on physicochemical and functional properties of peanut protein
Peanut protein isolate (PPI) solutions were modified by dielectric barrier discharge (DBD)
cold plasma (CP) treatment. Effects of CP treatment on the solubility, emulsion stability, and …
cold plasma (CP) treatment. Effects of CP treatment on the solubility, emulsion stability, and …
Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody
Despite technological advances, detection of deamidation in large proteins remains a
challenge and the use of orthogonal methods is needed for unequivocal assignment. By a …
challenge and the use of orthogonal methods is needed for unequivocal assignment. By a …
Separation and analysis of peptides and proteins
This review focuses on selected applications of the separation and analysis of peptides and
proteins published during the period of 1997-1998. Specific topic areas covered include …
proteins published during the period of 1997-1998. Specific topic areas covered include …
Temperature stability of proteins: Analysis of irreversible denaturation using isothermal calorimetry
A Schön, BR Clarkson, M Jaime… - … : Structure, Function, and …, 2017 - Wiley Online Library
The structural stability of proteins has been traditionally studied under conditions in which
the folding/unfolding reaction is reversible, since thermodynamic parameters can only be …
the folding/unfolding reaction is reversible, since thermodynamic parameters can only be …
[HTML][HTML] Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
Q Qu, Y Chen, Y Wang, W Wang, S Long, HY Yang… - Nature, 2024 - nature.com
Lithocholic acid (LCA) is accumulated in mammals during calorie restriction and it can
activate AMP-activated protein kinase (AMPK) to slow down ageing. However, the molecular …
activate AMP-activated protein kinase (AMPK) to slow down ageing. However, the molecular …
Heat‐induced denaturation and aggregation of ovalbumin at neutral pH described by irreversible first‐order kinetics
The heat‐induced denaturation kinetics of two different sources of ovalbumin at pH 7 was
studied by chromatography and differential scanning calorimetry. The kinetics was found to …
studied by chromatography and differential scanning calorimetry. The kinetics was found to …
Influence of calcium ions on the thermal characteristics of α-amylase from thermophilic Anoxybacillus sp. GXS-BL
SM Liao, GE Liang, J Zhu, BO Lu… - Protein and peptide …, 2019 - ingentaconnect.com
Background: α-Amylases are starch-degrading enzymes and used widely, the study on
thermostability of α-amylase is a central requirement for its application in life science and …
thermostability of α-amylase is a central requirement for its application in life science and …
Thermally induced conformational changes in horseradish peroxidase
Detailed differential scanning calorimetry (DSC), steady‐state tryptophan fluorescence and
far‐UV and visible CD studies, together with enzymatic assays, were carried out to monitor …
far‐UV and visible CD studies, together with enzymatic assays, were carried out to monitor …
DSC and electrophoretic studies on soymilk protein denaturation
H Zhang, M Takenaka, S Isobe - Journal of thermal analysis and …, 2004 - Springer
The effects of heat treatment on soymilk protein denaturation were studied by differential
scanning calorimetry (DSC) and electrophoresis. Transition behavior of soymilk was studied …
scanning calorimetry (DSC) and electrophoresis. Transition behavior of soymilk was studied …