Scalable fabrication and use of 3D structured microparticles spatially functionalized with biomolecules

S Lee, J de Rutte, R Dimatteo, D Koo, D Di Carlo - ACS nano, 2021 - ACS Publications
Microparticles with defined shapes and spatial chemical modification can interface with cells
and tissues at the cellular scale. However, conventional methods to fabricate shaped …

[HTML][HTML] Sorting single-cell microcarriers using commercial flow cytometers

J de Rutte, R Dimatteo, S Zhu, MM Archang, D Di Carlo - SLAS technology, 2022 - Elsevier
The scale of biological discovery is driven by the vessels in which we can perform assays
and analyze results, from multi-well plates to microfluidic compartments. We report on the …

Monodisperse drops templated by 3D-structured microparticles

CY Wu, M Ouyang, B Wang, J de Rutte, A Joo… - Science …, 2020 - science.org
The ability to create uniform subnanoliter compartments using microfluidic control has
enabled new approaches for analysis of single cells and molecules. However, specialized …

Engineering design of concentric amphiphilic microparticles for spontaneous formation of picoliter to nanoliter droplet volumes

G Destgeer, M Ouyang, D Di Carlo - Analytical Chemistry, 2021 - ACS Publications
Simple mixing of aqueous and oil solutions with amphiphilic particles leads to the
spontaneous formation of uniform reaction volumes (dropicles) that can enable numerous …

Interfacial tension driven open droplet microfluidics

JW Khor, UN Lee, J Berthier, E Berthier… - Advanced Materials …, 2023 - Wiley Online Library
Droplet microfluidics enables compartmentalized reactions in small scales and is utilized for
a variety of applications across chemical analysis, material science, and biology. While …

Statistical energy minimization theory for systems of drop-carrier particles

RS Du, L Liu, S Ng, S Sambandam… - Physical Review E, 2021 - APS
Drop-carrier particles (DCPs) are solid microparticles designed to capture uniform
microscale drops of a target solution without using costly microfluidic equipment and …

High-throughput selection of microalgae based on biomass accumulation rates in production environments using PicoShell Particles

M van Zee, J de Rutte, R Rumyan, C Williamson… - bioRxiv, 2021 - biorxiv.org
Production of high-energy lipids by microalgae may provide a sustainable, renewable
energy source that can help tackle climate change. However, microalgae engineered to …

[PDF][PDF] Minimal surface configurations for axisymmetric microparticles

K Ha, J de Rutte, D Di Carlo… - UCLA Comput. Appl …, 2020 - ww3.math.ucla.edu
An important area of microfluidics is the creation and manipulation of small droplets. This is
commonly done using microchannels or electrowetting. Recently a new method is proposed …

Scalable fabrication of 3D structured microparticles using induced phase separation

S Lee, J de Rutte, R Dimatteo, D Koo, D Di Carlo - bioRxiv, 2021 - biorxiv.org
Microparticles with defined shapes and spatial chemical modification can enable new
opportunities to interface with cells and tissues at the cellular scale. However, conventional …

[書籍][B] Microfabrication of Three-Dimensional Complex Structures for Biomedical Applications

S Lee - 2022 - search.proquest.com
The evolution of microfabrication has greatly contributed to the advances in biology and
medicine, as it can interface with and manipulate the interactions between biological …