The importance of Streptococcus mutans in the etiology and pathogenesis of dental caries is
certainly controversial, in part because excessive attention is paid to the numbers of S …

In eukaryotes, lactate produced during glycolysis is involved in regulating multiple metabolic
processes through lysine lactylation (Kla). To explore the potential link between metabolism …

Streptococcus mutans is a key contributor to the formation of the extracellular
polysaccharide (EPS) matrix in dental biofilms. The exopolysaccharides, which are mostly …

The in vivo composition of the mycelial extracellular matrix (ECM) of Aspergillus fumigatus
during host invasion is reported here for the first time. A new galactosaminogalactan and the …

The traditional concept of caries as a multifactorial transmittable and infectious disease has
been challenged. Novel conceptual ideas have come to add to the complexity of this highly …

Background Dental caries is a microbe and sugar-mediated biofilm-dependent oral disease.
Of particular significance, a virulent type of dental caries, known as severe early childhood …

Cranberry crude extracts, in various vehicles, have shown inhibitory effects on the formation
of oral biofilms in vitro. The presence of proanthocyanidins (PAC) in cranberry extracts has …

Mucus barriers accommodate trillions of microorganisms throughout the human body while
preventing pathogenic colonization. In the oral cavity, saliva containing the mucins MUC5B …

Understanding how the body's natural defenses function to protect the oral cavity from the
myriad of bacteria that colonize its surfaces is an ongoing topic of research that can lead to …

Aims: To investigate the structural organization and dynamics of exopolysaccharides (EPS)
matrix and microcolonies formation by Streptococcus mutans during the biofilm development …