[HTML][HTML] Exploring the synthesis, structure, spectroscopy and biological activities of novel 4-benzylidene-1-(2-(2, 4-dichloro phenyl) acetyl) thiosemicarbazide …

M Waheed, S Idris, F Jan, A Alam, M Ibrahim… - Saudi Pharmaceutical …, 2023 - Elsevier
Background Novel α-amylase inhibitors play a crucial role in managing diabetes and
obesity, contributing to improved public health by addressing these challenging and …

Antimicrobial and structural properties of metal ions complexes with thiosemicarbazide motif and related heterocyclic compounds

E Namiecińska, M Sobiesiak, M Małecka… - Current Medicinal …, 2019 - ingentaconnect.com
Antibiotic resistance acquired by various bacterial fungal and viral pathogens poses
therapeutic problems of increasing severity. Among the infections that are very difficult to …

Coumarin derivatives with potential anticancer and antibacterial activity: Design, synthesis, VEGFR‐2 and DNA gyrase inhibition, and in silico studies

SH Emam, RA Hassan, EO Osman… - Drug Development …, 2023 - Wiley Online Library
A series of coumarin derivatives were designed, synthesized, and evaluated for their
antiproliferative activity. Compound 3e exhibited significant antiproliferative activity and was …

Synthesis and characterization of thiosemicarbazone metal complexes: Crystal structure, and antiproliferation activity against breast (MCF7) and lung (A549) cancers

MS Ali, FA El-Saied, MME Shakdofa, S Karnik… - Journal of Molecular …, 2023 - Elsevier
Thiosemicarbazone compound has pronounced anticancer activity, which increases by
metal ions presence. New Ni (II), Cu (II), Pd (II), and Pt (II) complexes synthesized from 2-(2 …

[HTML][HTML] Design, synthesis, and biological evaluation of novel 1, 3, 4-thiadiazole derivatives as potential antitumor agents against chronic myelogenous leukemia …

MD Altıntop, HI Ciftci, MO Radwan, B Sever… - Molecules, 2017 - mdpi.com
In an attempt to develop potent antitumor agents, new 1, 3, 4-thiadiazole derivatives were
synthesized and evaluated for their cytotoxic effects on multiple human cancer cell lines …

Discovering the anti-diabetic potential of thiosemicarbazone derivatives: In vitro α-glucosidase, α-amylase inhibitory activities with molecular docking and DFT …

S Gul, AA Elhenawy, Q Ali, MU Rehman, A Alam… - Journal of Molecular …, 2024 - Elsevier
This work describes the synthesis of para-substituted thiosemicarbazone derivatives by
refluxing 4-ethoxybenzaldehyde (1) and 4-nitrobenzaldehyde (2) with thiosemicarbazide in …

Synthesis, Structure, and Biologic Activity of Some Copper, Nickel, Cobalt, and Zinc Complexes with 2‐Formylpyridine N4‐Allylthiosemicarbazone

V Graur, Y Chumakov, O Garbuz… - Bioinorganic …, 2022 - Wiley Online Library
A series of zinc (II)([Zn (H2O)(L) Cl](1)), copper (II)([Cu (L) Cl](2),[Cu (L) Br](3),[Cu2 (L) 2
(CH3COO) 2]· 4H2O (4)), nickel (II)([Ni (HL) 2] Cl2· H2O (5)), and cobalt (III)([Co (L) 2] Cl (6)) …

Design, synthesis, cytotoxic screening and molecular docking studies of novel hybrid thiosemicarbazone derivatives as anticancer agents

FZ Mohammed, YW Rizzk, IM El Deen… - Chemistry & …, 2021 - Wiley Online Library
Thiosemicarbazones have been the focus of scientists owing to their broad clinical
anticancer range. Herein, A Series of new thiosemicarbazone derivatives 5–9 were …

Synthesis, characterization, antioxidant and antiparasitic activities new naphthyl-thiazole derivatives

NFN Santos, NSB Junior, JF de Oliveira… - Experimental …, 2023 - Elsevier
Abstract In this work, 13 thiosemicarbazones (1a–m) and 16 thiazoles (2a–p) were obtained,
which were properly characterized by spectroscopic and spectrometric techniques. The …

Copper (I) and silver (I) complexes of anthraldehyde thiosemicarbazone: synthesis, structure elucidation, in vitro anti-tuberculosis/cytotoxic activity and interactions …

A Khan, K Paul, I Singh, JP Jasinski… - Dalton …, 2020 - pubs.rsc.org
A reaction of copper (I) halides (X= I, Br, Cl) and silver (I) halides with 9-anthraldehyde
thiosemicarbazone (9-Hanttsc, H1L) and triphenylphosphine produced halogen-bridged …