Novel insights into the interplay between m6A modification and noncoding RNAs in cancer

YC Yi, XY Chen, J Zhang, JS Zhu - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …

[HTML][HTML] The IGF2BP family of RNA binding proteins links epitranscriptomics to cancer

D Ramesh-Kumar, S Guil - Seminars in Cancer Biology, 2022 - Elsevier
RNA binding proteins that act at the post-transcriptional level display a richness of
mechanisms to modulate the transcriptional output and respond to changing cellular …

A novel hypoxic long noncoding RNA KB-1980E6. 3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability

P Zhu, F He, Y Hou, G Tu, Q Li, T **, H Zeng, Y Qin… - Oncogene, 2021 - nature.com
The hostile hypoxic microenvironment takes primary responsibility for the rapid expansion of
breast cancer tumors. However, the underlying mechanism is not fully understood. Here …

m6A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2‐mediated IGF1R mRNA stabilization

C Lang, C Yin, K Lin, Y Li, Q Yang, Z Wu… - Clinical and …, 2021 - Wiley Online Library
Background Bone metastasis is the leading cause of tumor‐related death in prostate cancer
(PCa) patients. Long noncoding RNAs (lncRNAs) have been well documented to be …

LncRNA GATA3‐AS1 facilitates tumour progression and immune escape in triple‐negative breast cancer through destabilization of GATA3 but stabilization of PD‐L1

M Zhang, N Wang, P Song, Y Fu, Y Ren, Z Li… - Cell …, 2020 - Wiley Online Library
Abstract Objectives Long non‐coding RNAs (lncRNAs) have been demonstrated as crucial
regulators in cancer, but whether they are involved in the immune response of cancer cells …

[HTML][HTML] Emerging roles of lncRNAs in the post-transcriptional regulation in cancer

RZ He, DX Luo, YY Mo - Genes & diseases, 2019 - Elsevier
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) can play a pivotal
role in regulation of diverse cellular processes. In particular, lncRNAs can serve as master …

The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription

A **a, W Yuan, Q Wang, J Xu, Y Gu, L Zhang, C Chen… - Nature cancer, 2022 - nature.com
Cancer-testis (CT) genes participate in the initiation and progression of cancer, but the role
of CT-associated long non-coding RNAs (CT-lncRNAs) in hepatocellular carcinoma (HCC) …

The role of lncRNAs in gene expression regulation through mRNA stabilization

M Sebastian-delaCruz, I Gonzalez-Moro… - Non-coding RNA, 2021 - mdpi.com
mRNA stability influences gene expression and translation in almost all living organisms,
and the levels of mRNA molecules in the cell are determined by a balance between …

[HTML][HTML] m6A-induced lncDBET promotes the malignant progression of bladder cancer through FABP5-mediated lipid metabolism

P Liu, B Fan, B Othmane, J Hu, H Li, Y Cui, Z Ou… - Theranostics, 2022 - ncbi.nlm.nih.gov
The limited effect of adjuvant therapy for advanced bladder cancer (BCa) leads to a poor
prognosis. Increasing evidence has shown that RNA N6-methyladenosine (m 6 A) …

LncRNA FOXP4-AS1 is activated by PAX5 and promotes the growth of prostate cancer by sequestering miR-3184-5p to upregulate FOXP4

X Wu, Y **ao, Y Zhou, Z Zhou, W Yan - Cell death & disease, 2019 - nature.com
Prostate cancer (PCa) is one of the major men malignancies worldwide. Long noncoding
RNAs (lncRNAs) have been reported as essential regulators in human cancers, including …