1H-Detected Biomolecular NMR under Fast Magic-Angle Spinning

T Le Marchand, T Schubeis, M Bonaccorsi… - Chemical …, 2022 - ACS Publications
Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

Amyloid-type protein aggregation and prion-like properties of amyloids

D Willbold, B Strodel, GF Schröder, W Hoyer… - Chemical …, 2021 - ACS Publications
This review will focus on the process of amyloid-type protein aggregation. Amyloid fibrils are
an important hallmark of protein misfolding diseases and therefore have been investigated …

Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases

H Zhang, X Ji, P Li, C Liu, J Lou, Z Wang… - Science China Life …, 2020 - Springer
Cells are compartmentalized by numerous membrane-enclosed organelles and
membraneless compartments to ensure that a wide variety of cellular activities occur in a …

A guide to studying protein aggregation

JAJ Housmans, G Wu, J Schymkowitz… - The FEBS …, 2023 - Wiley Online Library
Disrupted protein folding or decreased protein stability can lead to the accumulation of
(partially) un‐or misfolded proteins, which ultimately cause the formation of protein …

Protein fibrils from different food sources: A review of fibrillation conditions, properties, applications and research trends

Y Meng, Z Wei, C Xue - Trends in Food Science & Technology, 2022 - Elsevier
Background In recent years, protein fibrillization has attracted extensive attention on account
of endowing food with desirable functional properties and better stability, which makes it a …

Biomolecular and biological applications of solid-state NMR with dynamic nuclear polarization enhancement

WY Chow, G De Paëpe, S Hediger - Chemical Reviews, 2022 - ACS Publications
Solid-state NMR spectroscopy (ssNMR) with magic-angle spinning (MAS) enables the
investigation of biological systems within their native context, such as lipid membranes, viral …

Amyloid cross-seeding: Mechanism, implication, and inhibition

S Subedi, S Sasidharan, N Nag, P Saudagar, T Tripathi - Molecules, 2022 - mdpi.com
Most neurodegenerative diseases such as Alzheimer's disease, type 2 diabetes, Parkinson's
disease, etc. are caused by inclusions and plaques containing misfolded protein …

High-resolution probing of early events in amyloid-β aggregation related to Alzheimer's disease

BR Sahoo, SJ Cox, A Ramamoorthy - Chemical Communications, 2020 - pubs.rsc.org
In Alzheimer's disease (AD), soluble oligomers of amyloid-β (Aβ) are emerging as a crucial
entity in driving disease progression as compared to insoluble amyloid deposits. The lacuna …

[BOOK][B] Bioinorganic chemistry: a short course

RM Roat-Malone - 2007 - books.google.com
An updated, practical guide to bioinorganic chemistry Bioinorganic Chemistry: A Short
Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry …

Dipolar Recoupling in Rotating Solids

V Ladizhansky, RS Palani, M Mardini… - Chemical …, 2024 - ACS Publications
Magic angle spinning (MAS) nuclear magnetic resonance (NMR) has evolved significantly
over the past three decades and established itself as a vital tool for the structural analysis of …