Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024‏ - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Stimuli-responsive nanobubbles for biomedical applications

R **ong, RX Xu, C Huang, S De Smedt… - Chemical Society …, 2021‏ - pubs.rsc.org
Stimuli-responsive nanobubbles have received increased attention for their application in
spatial and temporal resolution of diagnostic techniques and therapies, particularly in …

Ingestible electronics for diagnostics and therapy

C Steiger, A Abramson, P Nadeau… - Nature Reviews …, 2019‏ - nature.com
The gastrointestinal (GI) tract offers the opportunity to detect physiological and
pathophysiological signals from the human body. Ingestible electronics can gain close …

Ultrasound modulates ion channel currents

J Kubanek, J Shi, J Marsh, D Chen, C Deng, J Cui - Scientific reports, 2016‏ - nature.com
Transcranial focused ultrasound (US) has been demonstrated to stimulate neurons in
animals and humans, but the mechanism of this effect is unknown. It has been hypothesized …

Sonogenetics is a non-invasive approach to activating neurons in Caenorhabditis elegans

S Ibsen, A Tong, C Schutt, S Esener… - Nature …, 2015‏ - nature.com
A major challenge in neuroscience is to reliably activate individual neurons, particularly
those in deeper brain regions. Current optogenetic approaches require invasive surgical …

A review on biological effects of ultrasounds: key messages for clinicians

CMI Quarato, D Lacedonia, M Salvemini, G Tuccari… - Diagnostics, 2023‏ - mdpi.com
Ultrasound (US) is acoustic energy that interacts with human tissues, thus, producing
bioeffects that may be hazardous, especially in sensitive organs (ie, brain, eye, heart, lung …

Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound

RE Apfel, CK Holland - Ultrasound in medicine & biology, 1991‏ - Elsevier
Although no deleterious effects from diagnostic ultrasound have been reported in
epidemiologic studies and surveys of widespread clinical usage (Ziskin and Petitti 1988), the …

Free radical formation induced by ultrasound and its biological implications

P Riesz, T Kondo - Free Radical Biology and Medicine, 1992‏ - Elsevier
The chemical effects of ultrasound in aqueous solutions are due to acoustic cavitation, which
refers to the formation, growth, and collapse of small gas bubbles in liquids. The very high …

Probability of cavitation for single ultrasound pulses applied to tissues and tissue-mimicking materials

AD Maxwell, CA Cain, TL Hall, JB Fowlkes… - Ultrasound in medicine & …, 2013‏ - Elsevier
In this study, the negative pressure values at which inertial cavitation consistently occurs in
response to a single, two-cycle, focused ultrasound pulse were measured in several media …

Doxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery …

P Mohan, N Rapoport - Molecular pharmaceutics, 2010‏ - ACS Publications
Doxorubicin (DOX) is one of the most commonly used chemotherapeutic drugs and is a
popular research tool due to the inherent fluorescence of the DOX molecule. After DOX …