The impact of PARPs and ADP-ribosylation on inflammation and host–pathogen interactions
Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a
highly conserved, fundamental posttranslational modification (PTM). PARP catalytic …
highly conserved, fundamental posttranslational modification (PTM). PARP catalytic …
Targeted restriction of viral gene expression and replication by the ZAP antiviral system
M Ficarelli, SJD Neil, CM Swanson - Annual Review of Virology, 2021 - annualreviews.org
The zinc finger antiviral protein (ZAP) restricts the replication of a broad range of RNA and
DNA viruses. ZAP directly binds viral RNA, targeting it for degradation and inhibiting its …
DNA viruses. ZAP directly binds viral RNA, targeting it for degradation and inhibiting its …
N (6)‐methyladenosine‐binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay
TL **a, X Li, X Wang, YJ Zhu, H Zhang, W Cheng… - EMBO …, 2021 - embopress.org
Abstract N 6‐methyladenosine (m6A) modification of mRNA mediates diverse cellular and
viral functions. Infection with Epstein–Barr virus (EBV) is causally associated with …
viral functions. Infection with Epstein–Barr virus (EBV) is causally associated with …
Inhibition of hepatitis B virus replication by the host zinc finger antiviral protein
R Mao, H Nie, D Cai, J Zhang, H Liu, R Yan… - PLoS …, 2013 - journals.plos.org
The zinc finger antiviral protein (ZAP) is a mammalian host restriction factor that inhibits the
replication of a variety of RNA viruses, including retroviruses, alphaviruses and filoviruses …
replication of a variety of RNA viruses, including retroviruses, alphaviruses and filoviruses …
ADP-ribosyltransferases and poly ADP-ribosylation
C Liu, X Yu - Current Protein and Peptide Science, 2015 - ingentaconnect.com
Protein ADP-ribosylation is an important posttranslational modification that plays versatile
roles in multiple biological processes. ADP-ribosylation is catalyzed by a group of enzymes …
roles in multiple biological processes. ADP-ribosylation is catalyzed by a group of enzymes …
Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus
H Jiao, Z Yan, X Zhai, Y Yang, N Wang, X Li… - Journal of …, 2023 - Am Soc Microbiol
Alphaviruses are emerging and re-emerging viruses that cause severe disease and threaten
public health worldwide. To advance the understanding of the underlying mechanisms of …
public health worldwide. To advance the understanding of the underlying mechanisms of …
PARP13 regulates cellular mRNA post-transcriptionally and functions as a pro-apoptotic factor by destabilizing TRAILR4 transcript
T Todorova, FJ Bock, P Chang - Nature communications, 2014 - nature.com
Abstract Poly (ADP-ribose) polymerase-13 (PARP13/ZAP/ZC3HAV1) is an antiviral factor,
active against specific RNA viruses such as murine leukaemia virus, Sindbis virus and …
active against specific RNA viruses such as murine leukaemia virus, Sindbis virus and …
Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells
C Peng, LS Wyatt, SG Glushakow-Smith… - PLoS …, 2020 - journals.plos.org
Modified vaccinia virus Ankara (MVA) is an approved smallpox vaccine and a promising
vaccine vector for other pathogens as well as for cancer therapeutics with more than 200 …
vaccine vector for other pathogens as well as for cancer therapeutics with more than 200 …
Poly (ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer
T Todorova, FJ Bock, P Chang - Trends in molecular medicine, 2015 - cell.com
Post-transcriptional regulation of RNA is an important mechanism for activating and
resolving cellular stress responses. Poly (ADP-ribose) polymerase-13 (PARP13), also …
resolving cellular stress responses. Poly (ADP-ribose) polymerase-13 (PARP13), also …
Poly (ADP-ribose) polymerases in host-pathogen interactions, inflammation, and immunity
PN Brady, A Goel, MA Johnson - Microbiology and molecular …, 2019 - Am Soc Microbiol
The literature review presented here details recent research involving members of the poly
(ADP-ribose) polymerase (PARP) family of proteins. Among the 17 recognized members of …
(ADP-ribose) polymerase (PARP) family of proteins. Among the 17 recognized members of …