[HTML][HTML] The fate of heterogeneous catalysis & click chemistry for 1, 2, 3-triazoles: Nobel prize in chemistry 2022

V Kumar, K Lal, RK Tittal - Catalysis Communications, 2023 - Elsevier
The demand for environmental friendly methodologies had shifted the the approach of
scientific community for using easy and green reaction conditions instead of using …

1, 2, 3-Triazole-containing hybrids with potential antibacterial activity against ESKAPE pathogens

C Deng, H Yan, J Wang, K Liu, B Liu, Y Shi - European Journal of …, 2022 - Elsevier
ESKAPE pathogens, as priority 1 and 2 pathogens, are prevalent infectious agents
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …

1, 2, 3-Triazoles of 8-hydroxyquinoline and HBT: Synthesis and studies (DNA binding, antimicrobial, molecular docking, ADME, and DFT)

N Nehra, RK Tittal, VD Ghule - ACS omega, 2021 - ACS Publications
A new series of 1, 2, 3-triazole hybrids containing either 2-or 4-hydroxyphenyl benzothiazole
(2-or 4-HBT) and naphthalen-1-ol or 8-hydroxyquinoline (8-HQ) was synthesized in high …

Indole-chalcone linked 1, 2, 3-triazole hybrids: Facile synthesis, antimicrobial evaluation and docking studies as potential antimicrobial agents

M Yadav, K Lal, A Kumar, A Kumar, D Kumar - Journal of Molecular …, 2022 - Elsevier
The design and synthesis of a new series of indole-chalcone linked 1, 2, 3-triazole hybrids
via Cu (Ι)-catalyzed azide-alkyne cycloaddition is reported. All the compounds (2, 4a–4e and …

Synthesis, characterization, α-glucosidase inhibition and molecular modeling studies of some pyrazoline-1H-1, 2, 3-triazole hybrids

L Kumar, K Lal, P Yadav, A Kumar, AK Paul - Journal of Molecular Structure, 2020 - Elsevier
A series of molecular hybrids based on pyrazoline and 1, 2, 3-triazole pharmacophores
were designed and synthesized as antidiabetic agents. The structures of all the derivatives …

Fluorescent 7-azaindole N-linked 1, 2, 3-triazole: synthesis and study of antimicrobial, molecular docking, ADME and DFT properties

K Sharma, RK Tittal, K Lal, RS Mathpati - New Journal of Chemistry, 2023 - pubs.rsc.org
Two libraries of biologically essential and fluorescent 7-azaindole N-linked benzyl 1, 2, 3-
triazole (4a–4i) and 7-azaindole N-linked phenyl 1, 2, 3-triazole (4j–4q) hybrids have been …

Synthesis, antifungal studies, molecular docking, ADME and DNA interaction studies of 4-hydroxyphenyl benzothiazole linked 1, 2, 3-triazoles

N Nehra, RK Tittal, DG Vikas, K Lal - Journal of Molecular Structure, 2021 - Elsevier
In search of new bioactive 1, 2, 3-triazole hybrids, some 4-hydroxyphenyl benzothiazole (4-
HBT) linked 1, 2, 3-triazole with varying lengths of alkyl spacers were synthesized from …

Dimethoxyindoles based thiosemicarbazones as multi-target agents; synthesis, crystal interactions, biological activity and molecular modeling

M Yıldız, M Bingul, Y Zorlu, MF Saglam, M Boga… - Bioorganic …, 2022 - Elsevier
Alzheimer's disease (AD) is known as one of the most devastating neurodegenerative
disease diagnosed for the old-aged people and cholinesterase inhibitors (ChEI) can be …

Novel 1, 2, 3‐Triazole Derivatives as Potential Inhibitors against Covid‐19 Main Protease: Synthesis, Characterization, Molecular Docking and DFT Studies

MR Aouad, DJO Khan, MA Said, NS Al‐Kaff… - …, 2021 - Wiley Online Library
The highly contagious nature of Covid‐19 attracted us to this challenging area of research,
mainly because the disease is spreading very fast and until now, no effective method of a …

Synthesis of novel tritopic hydrazone ligands: spectroscopy, biological activity, DFT, and molecular docking studies

SA Rupa, MR Moni, MAM Patwary, MM Mahmud… - Molecules, 2022 - mdpi.com
Polytopic organic ligands with hydrazone moiety are at the forefront of new drug research
among many others due to their unique and versatile functionality and ease of strategic …