[HTML][HTML] Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification

AJ Seukep, V Kuete, L Nahar, SD Sarker… - Journal of pharmaceutical …, 2020 - Elsevier
The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …

Integration of high-throughput omics technologies in medicinal plant research: The new era of natural drug discovery

W Zhang, Y Zeng, M Jiao, C Ye, Y Li, C Liu… - Frontiers in Plant …, 2023 - frontiersin.org
Medicinal plants are natural sources to unravel novel bioactive compounds to satisfy human
pharmacological potentials. The world's demand for herbal medicines is increasing year by …

[HTML][HTML] Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants

MT ul Qamar, SM Alqahtani, MA Alamri… - Journal of pharmaceutical …, 2020 - Elsevier
The recent pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has
raised global health concerns. The viral 3-chymotrypsin-like cysteine protease (3CL pro) …

[HTML][HTML] Promising terpenes as SARS-CoV-2 spike receptor-binding domain (RBD) attachment inhibitors to the human ACE2 receptor: Integrated computational …

ZT Muhseen, AR Hameed, HMH Al-Hasani… - Journal of molecular …, 2020 - Elsevier
The spike protein receptor binding domain (S-RBD) is a necessary corona-viral protein for
binding and entry of coronaviruses (COVs) into the host cells. Hence, it has emerged as an …

Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CLpro

MA Alamri, M Tahir ul Qamar, MU Mirza… - Journal of …, 2021 - Taylor & Francis
The SARS-CoV-2 was confirmed to cause the global pandemic of coronavirus disease 2019
(COVID-19). The 3-chymotrypsin-like protease (3CLpro), an essential enzyme for viral …

Computational screening of medicinal plant phytochemicals to discover potent pan-serotype inhibitors against dengue virus

M Tahir ul Qamar, A Maryam, I Muneer, F ** medicinal herbs databases
Z Fathifar, LR Kalankesh, A Ostadrahimi, R Ferdousi - Database, 2023 - academic.oup.com
Medicinal herbs databases have become a crucial part of organizing new scientific literature
generated in medicinal herbs field, as well as new drug discoveries in the information era …