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Immunology of Mycobacterium tuberculosis Infections
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
BCG-induced cross-protection and development of trained immunity: implication for vaccine design
The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the
ability to induce non-specific cross-protection against pathogens that might be unrelated to …
ability to induce non-specific cross-protection against pathogens that might be unrelated to …
Tuberculosis and HIV co-infection
A Pawlowski, M Jansson, M Sköld… - PLoS …, 2012 - journals.plos.org
Tuberculosis (TB) and HIV co-infections place an immense burden on health care systems
and pose particular diagnostic and therapeutic challenges. Infection with HIV is the most …
and pose particular diagnostic and therapeutic challenges. Infection with HIV is the most …
Mycobacterium tuberculosis: immune response, biomarkers, and therapeutic intervention
L Zhuang, L Yang, L Li, Z Ye, W Gong - MedComm, 2024 - Wiley Online Library
Although tuberculosis (TB) is an infectious disease, the progression of the disease following
Mycobacterium tuberculosis (MTB) infection is closely associated with the host's immune …
Mycobacterium tuberculosis (MTB) infection is closely associated with the host's immune …
Mycobacterium tuberculosis Pathogenesis and Molecular Determinants of Virulence
I Smith - Clinical microbiology reviews, 2003 - journals.asm.org
Tuberculosis (TB), one of the oldest known human diseases. is still is one of the major
causes of mortality, since two million people die each year from this malady. TB has many …
causes of mortality, since two million people die each year from this malady. TB has many …
Cell-mediated immune responses in tuberculosis
Tuberculosis is primarily a disease of the lung, and dissemination of the disease depends
on productive infection of this critical organ. Upon aerosol infection with Mycobacterium …
on productive infection of this critical organ. Upon aerosol infection with Mycobacterium …
Mycobacteria target DC-SIGN to suppress dendritic cell function
TBH Geijtenbeek, SJ Van Vliet, EA Koppel… - The Journal of …, 2003 - rupress.org
Mycobacterium tuberculosis represents a world-wide health risk and immunosuppression is
a particular problem in M. tuberculosis infections. Although macrophages are primarily …
a particular problem in M. tuberculosis infections. Although macrophages are primarily …
DC-SIGN: escape mechanism for pathogens
Y van Kooyk, TBH Geijtenbeek - Nature Reviews Immunology, 2003 - nature.com
Dendritic cells (DCs) are crucial in the defence against pathogens. Invading pathogens are
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …
Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors
Mycobacterium tuberculosis survives in antigen-presenting cells (APCs) such as
macrophages and dendritic cells. APCs present antigens in association with major …
macrophages and dendritic cells. APCs present antigens in association with major …
Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo
Mycobacterium tuberculosis (Mtb) is thought to reside in macrophages, although infected
dendritic cells (DCs) have been observed. Thus, although cellular associations have been …
dendritic cells (DCs) have been observed. Thus, although cellular associations have been …