• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

The focus of the “2014 AHA/ACC Guideline for the Management of Patients With Valvular
Heart Disease” 9, 10 (2014 VHD guideline) was the diagnosis and management of adult …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Infective endocarditis is defined by a focus of infection within the heart and is a feared
disease across the field of cardiology. It is frequently acquired in the health care setting, and …

The American College of Cardiology (ACC) develops a number of clinical policy documents
to provide members with guidance on clinical topics. Although clinical practice guidelines …

Importance Limited data exist on clinical characteristics and outcomes of patients who had
infective endocarditis after undergoing transcatheter aortic valve replacement (TAVR) …

Abstract Purpose of the Review Infective endocarditis (IE) is a relatively infrequent infectious
disease. It does, however, causes serious morbidity, and its mortality rate has remained …

Infective endocarditis (IE) is a rare but serious complication following transcatheter aortic
valve replacement (TAVR). Despite substantial improvements in the TAVR procedure (less …