The neurobiological basis of human aggression: a review on genetic and epigenetic mechanisms

R Waltes, AG Chiocchetti… - American Journal of …, 2016 - Wiley Online Library
Aggression is an evolutionary conserved behavior present in most species including
humans. Inadequate aggression can lead to long‐term detrimental personal and societal …

Neurogenetics of aggressive behavior: studies in rodents

A Takahashi, KA Miczek - Neuroscience of aggression, 2014 - Springer
Aggressive behavior is observed in many animal species, such as insects, fish, lizards,
frogs, and most mammals including humans. This wide range of conservation underscores …

The role of monoamine oxidase A in the neurobiology of aggressive, antisocial, and violent behavior: A tale of mice and men

NJ Kolla, M Bortolato - Progress in neurobiology, 2020 - Elsevier
Over the past two decades, research has revealed that genetic factors shape the propensity
for aggressive, antisocial, and violent behavior. The best-documented gene implicated in …

Genetics of aggressive behavior: an overview

K Veroude, Y Zhang‐James… - American Journal of …, 2016 - Wiley Online Library
The Research Domain Criteria (RDoC) address three types of aggression: frustrative non‐
reward, defensive aggression and offensive/proactive aggression. This review sought to …

A systematic review and meta-analysis examining the interrelationships between chemical and non-chemical stressors and inherent characteristics in children with …

FM Nilsen, NS Tulve - Environmental research, 2020 - Elsevier
Children may be more vulnerable to the combined interactions of chemical and non-
chemical stressors from their built, natural, and social environments when compared to …

The role of monoamine oxidase A in aggression: Current translational developments and future challenges

SC Godar, PJ Fite, KM McFarlin, M Bortolato - Progress in neuro …, 2016 - Elsevier
Drawing upon the recent resurgence of biological criminology, several studies have
highlighted a critical role for genetic factors in the ontogeny of antisocial and violent conduct …

Monoamine oxidase A and A/B knockout mice display autistic-like features

M Bortolato, SC Godar, L Alzghoul… - International Journal …, 2013 - academic.oup.com
Converging lines of evidence show that a sizable subset of autism-spectrum disorders
(ASDs) is characterized by increased blood levels of serotonin (5-hydroxytryptamine, 5-HT) …

Association of low-activity MAOA allelic variants with violent crime in incarcerated offenders

DA Stetler, C Davis, K Leavitt, I Schriger… - Journal of psychiatric …, 2014 - Elsevier
The main enzyme for serotonin degradation, monoamine oxidase (MAO) A, has recently
emerged as a key biological factor in the predisposition to impulsive aggression. Male …

The role of the serotonergic system at the interface of aggression and suicide

M Bortolato, N Pivac, DM Seler, MN Perkovic, M Pessia… - Neuroscience, 2013 - Elsevier
Alterations in serotonin (5-HT) neurochemistry have been implicated in the aetiology of all
major neuropsychiatric disorders, ranging from schizophrenia to mood and anxiety-spectrum …

Drugs related to monoamine oxidase activity

Z Fišar - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
Progress in understanding the role of monoamine neurotransmission in pathophysiology of
neuropsychiatric disorders was made after the discovery of the mechanisms of action of …